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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2438 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2438)
2438 Results for "decrease" in MCE Product Catalog:
Referencia número: HY-110020
No. CAS: 851320-29-1
Target:
Áreas de investigación:
rel-O-2050 (Compound O-2050) is a neutral cannabinoid CB1 receptor antagonist. rel-O-2050 also decreases food intake in mice .
Referencia número: HY-111308
No. CAS: 847554-50-1
Target:
Áreas de investigación:
RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration .
Referencia número: HY-117805
No. CAS: 177847-28-8
Target:
Áreas de investigación:
UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow .
Referencia número: HY-119926
No. CAS: 15358-48-2
Synonyms: Hydroxylupanine
Target:
Áreas de investigación:
13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .
Referencia número: HY-119926A
No. CAS: 6809-89-8
Synonyms: Hydroxylupanine hydrochloride
Target:
Referencia número: HY-126852
No. CAS: 163217-70-7
Synonyms: P-Hydroxyatorvastatin lactone; 4-ATL
Target:
Áreas de investigación:
4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids .
Referencia número: HY-136676
No. CAS: 122088-76-0
Cgp 38560 methanesulfonate is a well-tolerated renin inhibitor. Cgp 38560 methanesulfonate caused a dose-dependent decrease in angiotensin II and plasma renin activity, and a dose-dependent increase in active renin.
Referencia número: HY-147327
No. CAS: 26367-45-3
Target:
Áreas de investigación:
N-Formylsarcolysine has antitumor activity, and inhibits leukemia by increasing the Hb and erythrocyte levels and decreasing the number of leukocytes. N-Formylsarcolysine also involves in glioblastoma and other diseases research .
Synonyms: N-Alloc doxorubicin
Áreas de investigación:
Alloc-DOX (N-Alloc doxorubicin) is a Doxorubicin (HY-15142A) prodrug. The combination of a catalyst (such as nano-palladium) and alloc-DOX leads to a decrease in cell viability and tumour growth .
Referencia número: HY-163279
No. CAS: 885902-66-9
Target:
Áreas de investigación:
Fluopipamine is an antagonist for Cellulose Synthase 1 (CESA1) with an IC50 of 0.78 μM. Fluopipamine leads a decrease in glucose uptake into cellulose and hyperaccumulation of CESAs at the PM in etiolated Arabidopsis seedlings .
Referencia número: HY-179114
No. CAS: 1211788-57-6
Target:
Áreas de investigación:
VU0519975 is a raft destabilizing compound. VU0519975 reduces PMP22 raft partitioning and destabilizes ordered domains. VU0519975 significantly decreases the fraction of phase separated GPMVs .
Referencia número: HY-180958
No. CAS: 3104316-26-6
Chlorohexane-PEG-clozapine is a HaloTag PROTAC degrader based on Clozapine (HY-14539). Chlorohexane-PEG-clozapine leads to a significant decrease in the luminescence intensity and protein level of Halo-Eluc .
Referencia número: HY-B0606A
No. CAS: 59985-21-6
Synonyms: INS365 free base
Áreas de investigación:
Diquafosol (INS365 free base) is a potent P2Y2 agonist. Diquafosol nhibits apoptosis and decreases ROS generation. Diquafosol has the potential for the research of dry eye .
Referencia número: HY-N7646
No. CAS: 143601-09-6
Category:
Plant Other Diseases Amaryllidaceae Extract Phenols Polyphenols Hypoxidaceae Extract Disease Research Fields Curculigo orchioides Gaertn. Extract
Target:
Referencia número: HY-P3637
No. CAS: 2640019-27-6
Target:
Áreas de investigación:
Referencia número: HY-P99627
No. CAS: 1708936-80-4
Synonyms: NV-02; PG110; ABT-110
Target:
Áreas de investigación:
Referencia número: HY-116953
No. CAS: 98049-69-5
Synonyms: LXB4
Target:
Áreas de investigación:
Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways .
The product specifications provided below refer solely to the active content of Lipoxin B4.
The product specifications provided below refer solely to the active content of Lipoxin B4.
Referencia número: HY-120152
No. CAS: 1449765-82-5
Target:
Áreas de investigación:
SLP7111228 is a selective sphingosine kinase 1 (SphK1) inhibitor and anti-inflammatory agent. SLP7111228 selectively inhibits SphK1 and reduces the production of sphingosine-1-phosphate. SLP7111228 decreases lipopolysaccharide-induced TNFα and IL-1β levels. SLP7111228 alleviates obliterative pulmonary arteriopathy, increases cardiac index and decreases total pulmonary vascular resistance index. SLP7111228 can be used in research related to neuroinflammatory diseases and pulmonary hypertension .
Target:
Áreas de investigación:
SLP7111228 hydrochloride is a selective sphingosine kinase 1 (SphK1) inhibitor and anti-inflammatory agent. SLP7111228 hydrochloride selectively inhibits SphK1 and reduces the production of sphingosine-1-phosphate. SLP7111228 hydrochloride decreases lipopolysaccharide-induced TNFα and IL-1β levels. SLP7111228 hydrochloride alleviates obliterative pulmonary arteriopathy, increases cardiac index and decreases total pulmonary vascular resistance index. SLP7111228 hydrochloride can be used in research related to neuroinflammatory diseases and pulmonary hypertension .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
