109 Results for "

complement component

" in MedChemExpress (MCE) Product Catalog:
Products (109)

109 Results for "complement component" in MCE Product Catalog:

10
10 Publications Verification
Referencia número: HY-P7863
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; complement component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
8
8 Cited Publications
Referencia número: HY-P1717
No. CAS: 1427001-89-5
Synonyms: Cp40
Áreas de investigación:  

Inflammation/Immunology

AMY-101 (Cp40), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation .
loading...
    loading...
8
8 Cited Publications
Referencia número: HY-P1717B
Synonyms: Cp40 acetate
Áreas de investigación:  

Inflammation/Immunology

AMY-101 acetate (Cp40 acetate), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 acetate (Cp40 acetate) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation .
loading...
    loading...
8
8 Cited Publications
Referencia número: HY-P1717A
No. CAS: 1789738-04-0
Synonyms: Cp40 TFA
Áreas de investigación:  

Inflammation/Immunology

AMY-101 TFA (Cp40 TFA), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation .
loading...
    loading...
7
7 Cited Publications
Referencia número: HY-P7862
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; complement component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 1; AHUS5; complement component C3a; ASP; complement component C3b
Species:  
Human
Source:  
E. coli
loading...
    loading...
7
7 Cited Publications
Referencia número: HY-P7695
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P81185
Synonyms: C5; C6; C7; C8; C9; complement component 5; complement component 6; complement component 7; complement component 8; complement component 9; MAC; Membrane attack complex; TCC; Terminal complement complex.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Rat

loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P74375
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C2; complement component 2; complement C2; complement Protein; C3/C5 Convertase; ARMD14; complement component C2; CO2
Species:  
Human
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P75464
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QB; complement Subcomponent C1q Chain B; complement C1q B Chain; complement C1q Chain B; complement component 1, Q Subcomponent, Beta Polypeptide; complement component C1q, B Chain; complement component 1, Q Subcomponent, B Chain; C1QD2; complement C1q
Species:  
Human
Source:  
Sf9 insect cells
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P71718
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QA; complement component 1, Q Subcomponent, A Chain; complement C1q A Chain; complement C1q Chain A; complement C1q Subcomponent Subunit A; complement component C1q, A Chain; complement component 1, Q Subcomponent, Alpha Polypeptide; C1QD1
Species:  
Mouse
Source:  
P. pastoris
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P7864
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Human
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P700862
Pureza:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Human
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P78247
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: C3; complement component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P7691
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD93; DJ737E23.1; Prev. C1QR1; ECSM3; Prev. MXRA4; Matrix-Remodeling-Associated Protein 4; C1qR(P); Matrix-Remodelling Associated 4; CDw93; C1qR; complement component 1 Q Subcomponent Receptor 1; complement component 1, Q Subcomponent, Receptor 1; Complem
Species:  
Human
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P76185
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QBP; Splicing Factor SF2-Associated Protein; Prev. HABP1; ASF/SF2-Associated Protein P32; complement component 1 Q Subcomponent-Binding Protein, Mitochondrial; Glycoprotein GC1qBP; Mitochondrial Matrix Protein P32; SF2AP32; Hyaluronan-Binding Protein 1
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
Referencia número: HY-P3502
No. CAS: 1841136-73-9
Synonyms: RA101495; RA3193
Target:  

Complement System

Áreas de investigación:  

Inflammation/Immunology

Zilucoplan (RA101495), a 15-amino acid macrocyclic peptide, is a potent complement component 5 (C5) inhibitor. Zilucoplan can be used in research of immune-mediated necrotising myopathy (IMNM) .
loading...
    loading...
Referencia número: HY-NP004
Synonyms: CVF
Cobra Venom Factor (CVF) is a selective activator targeting complement components C3, C5, and factor B in the complement system. After binding to factor B, Cobra Venom Factor is cleaved by factor D, forming a stable C3/C5 convertase resistant to regulatory proteins H and I. This continuously hydrolyzes C3 and C5, depleting serum complement while inducing neutrophil migration, vascular leakage, and increased TNF-α levels. Cobra Venom Factor can be used to deplete complement and mimic complement activation-related pathological states, and is applied in animal models of complement-mediated diseases such as acute respiratory distress syndrome (ARDS), sepsis, and shock. Cobra Venom Factor can be isolated from the venom of cobras (e.g., Naja atra, Naja melanoleuca, Naja kaouthia, etc.) .
loading...
    loading...
Referencia número: HY-P991127
No. CAS: 2922766-89-8
Synonyms: DNTH103

Target:  

Complement System

Áreas de investigación:  

Inflammation/Immunology

Claseprubart (DNTH103) is an inhibitor targeting C1s of the complement system and an inhibitor of the C1 component of the complement cascade. Claseprubart is in phase 2 clinical evaluation. Claseprubart has application potential in research related to multifocal motor neuropathy and generalized myasthenia gravis .
loading...
    loading...
Referencia número: HY-P99050
No. CAS: 2049079-64-1
Synonyms: BIVV009; IPN-009; TNT009

Target:  

Complement System

Áreas de investigación:  

Endocrinology

Sutimlimab is a humanized monoclonal IgG4 antibody. Sutimlimab inhibits complement protein component 1, s subcomponent (C1s). Sutimlimab blocks C3 and C4 activation. Sutimlimab can be used for the research of cold agglutinin disease and complement-mediated hemolytic uremic syndrome .
loading...
    loading...
Referencia número: HY-P99358
No. CAS: 1662664-56-3
Synonyms: GSK 2398852; Anti-Serum Amyloid P/SAP Reference Antibody (dezamizumab)

Target:  

Complement System

Áreas de investigación:  

Inflammation/Immunology

Dezamizumab (GSK 2398852) is a fully humanized clonal IgG1 antibody against serum amyloid P component (SAP) with complement activation and amyloid clearance-inducing activities. Dezamizumab binds to SAP associated with amyloid deposits to form complexes that activate complement and mediate phagocytic clearance, triggering activation of the classical complement pathway. Dezamizumab can be used for the research of systemic amyloidosis .
loading...
    loading...