SLCB050
SLCB050 is a compound that blocks the interaction between DX2 and p14/ARF and has anticancer activity. SLCB050 reduces the viability of human lung cancer cells, especially small cell lung cancer cells, in a p14/ARF-dependent manner and induces apoptosis and senescence.
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- No. CAS: 1848971-16-3
- Fòrmula: C21H18O6
- Peso molecular:366.36
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NSCLC | GI50 |
>50 μM
Compound: SLCB050
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Growth inhibition of human NSCLC
Growth inhibition of human NSCLC
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[PMID: 32208684] |
| SCLC | GI50 |
5 μM
Compound: SLCB050
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Inhibition of DX2-p14/ARF interaction in human SCLC cells assessed as inhibition of cell growth by MTT assay
Inhibition of DX2-p14/ARF interaction in human SCLC cells assessed as inhibition of cell growth by MTT assay
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[PMID: 32208684] |
Chemical Information
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No. CAS 1848971-16-3
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Peso molecular 366.36
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Fòrmula C21H18O6
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SMILES
CC1(OC2=CC(OC(C=C3)=O)=C3C=C2C[C@@H]1OC(/C=C/C4=CC=CO4)=O)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SLCB050 Related Classifications
HY-164536 Related Classifications
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