TAB29
TAB29 is a potent inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) with an IC50 of 874 nM, possesses therapeutic potential for human cancers.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2361144-71-8
- Fòrmula: C28H22O3
- Peso molecular:406.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
IC50:874 nM (Pin1)[1]
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| SK-HEP1 | IC50 |
1.14 μM
Compound: TAB29
|
Cytotoxicity against human SKHEP1 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human SKHEP1 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31027708] |
| SNU-423 | IC50 |
2.732 μM
Compound: TAB29
|
Cytotoxicity against human SNU423 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human SNU423 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31027708] |
Chemical Information
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No. CAS 2361144-71-8
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Peso molecular 406.47
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Fòrmula C28H22O3
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SMILES
C1(OCC2=CC=CC=C2)=CC(OCC3=CC=CC=C3)=C4C(OC=C4C5=CC=CC=C5)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)