THK-5117

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THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe.

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  • Pureza: 98.52%
  • No. CAS: 1374107-54-6
  • Fòrmula: C19H19FN2O2
  • Peso molecular:326.36
  • Almacenamiento:

    4°C, stored under nitrogen

    * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

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100 mg

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