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Referencia número: HY-120022

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THPP-2

THPP-2 is a tetrahydropyridopyrimidine-type phosphodiesterase 10A (PDE10A) inhibitor with a K_i of 94 nM. THPP-2 is applicable to the research of schizophrenia.

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No. CAS: 1393750-01-0
Fòrmula: C₂₇H₂₇N₇O
Peso molecular:465.56

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

THPP-2 Chemical Structure

No. CAS: 1393750-01-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

THPP-2 is a tetrahydropyridopyrimidine-type phosphodiesterase 10A (PDE10A) inhibitor with a K_i of 94 nM. THPP-2 is applicable to the research of schizophrenia^[1].

IC₅₀ & Target

^[1]

PDE10A

94 nM (Ki)

Ver todos los productos específicos de isoformas Phosphodiesterase (PDE) :

Chemical Information

No. CAS 1393750-01-0
Peso molecular 465.56
Fòrmula C₂₇H₂₇N₇O
SMILES

O=C(NC=1C=CC=CC1)N2CC=3C(=NC(=NC3CC2)C=4C=CN=CC4)N(C)CCC5=NC=CC=C5
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Raheem IT, et al. Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2012;22(18):5903-5908. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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THPP-2

Ver todos los productos específicos de isoformas Phosphodiesterase (PDE)

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THPP-2 Related Classifications

HY-120022 Related Classifications

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