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Referencia número: HY-148223

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Tolindate

Tolindate is a potent PXR agonist with an EC₅₀ value of 8.3 μM. Tolindate shows antifungal activity.

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No. CAS: 27877-51-6
Fòrmula: C₁₈H₁₉NOS
Peso molecular:297.41

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Tolindate Chemical Structure

No. CAS: 27877-51-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Tolindate is a potent PXR agonist with an EC₅₀ value of 8.3 μM. Tolindate shows antifungal activity^[1]^[2].

In Vitro

Tolindate (0-100 μM; 24 h) with the presence of SPA70 (0.5, 7.5 μM) shows significantly induces CYP3A4 in hPXR HepG2 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 27877-51-6
Peso molecular 297.41
Fòrmula C₁₈H₁₉NOS
SMILES

S=C(N(C)C1=CC=CC(C)=C1)OC2=CC=C3C(CCC3)=C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Lynch C, et al. Characterization of human pregnane X receptor activators identified from a screening of the Tox21 compound library. Biochem Pharmacol. 2021 Feb;184:114368. [Content Brief]

[2]. Pastor L, et al. New antifungals selected by molecular topology. Bioorg Med Chem Lett. 1998 Sep 22;8(18):2577-82. [Content Brief]

Calculators

Calculadora de molaridad

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Calculadora de dilución

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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