WR-27653
WR-27653 (RC-12) is a derivative of Catechol with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) model. WR-27653 has antimalarial activity.
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- No. CAS: 6042-36-0
- Fòrmula: C20H36BrN3O2
- Peso molecular:430.42
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 6042-36-0
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Peso molecular 430.42
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Fòrmula C20H36BrN3O2
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SMILES
BrC1=C(N(CCN(CC)CC)CCN(CC)CC)C=C(OC)C(OC)=C1
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Synonyms
RC-12
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Dong Y, et al. Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12). ACS Omega. 2022 Mar 30;7(14):12401-12411. [Content Brief]
[2]. Werbel LM, et al. Synthesis and physical properties of the antimalarial agent 4-(2-bromo-4,5-dimethoxyphenyl)-1,1,7,7-tetraethyldiethylenetriamine (RC-12) (WR-27,653). J Pharm Sci. 1967 Oct;56(10):1335-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)