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Zanidatamab

(Synonyms: ZW 25; ZW-49 Antibody)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Zanidatamab (ZW25) is a humanised, bispecific monoclonal antibody targeting 2 distinct HER2 epitopes (ECD2 and ECD4). Zanidatamab has anti-tumour activity.

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  • Pureza : 98.56%
  • No. CAS: 2169946-15-8
  • Peso molecular:124.65kDa
  • Almacenamiento:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Zanidatamab
  • Experimental Validation Results for Zanidatamab
  • Experimental Validation Results for Zanidatamab
  • Experimental Validation Results for Zanidatamab
  • Experimental Validation Results for Zanidatamab
  • Zanidatamab Chemical Structure
    Zanidatamab Chemical Structure
No. CAS: 2169946-15-8
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609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3

  • 1/16

    Loaded Zanidatamab on AHC2 biosensor, can bind HER2/CD340 Protein, Human (S310Y, HEK293, His, HY-P78680) with an affinity constant of 7.956E-11 M as determined in BLI assay.

  • 1/16

    Immobilized Zanidatamab can bind Human Her2/ERBB2 Protein (ECD, His Tag). The EC50 for this effect is 3.09 ng/mL.

  • 1/16

    Zanidatamab purchased from MedChemExpress. Usage Cited in: MAbs. 2024 Jan-Dec;16(1):2412881. [Abstract]

    Customer Validation
     Head-to-head comparison of KJ015, Zanidatamab (0.01-100 μg/mL, 120 h), and Anbenitamab in MDA-MB-175. All assays were repeated twice.

  • 1/16

    Zanidatamab purchased from MedChemExpress. Usage Cited in: MAbs. 2024 Jan-Dec;16(1):2412881. [Abstract]

    Customer Validation
     Immunoblots of cell lysates from SK-Br-3 and NCI-N87 cells treated with IgG, Trastuzumab, Pertuzumab, tras+pert, or KJ015 at a final concentration of 50 nM for 24 h. Extra groups of anbenitamab and zanidatamab were added at the same concentration in MDA-MB-175 cells. Actin served as the loading control. T: trastuzumab, P: pertuzumab, T+P: tras+pert, Anbe: anbenitamab, Zani: zanidatamab.

  • Zanidatamab Chemical Structure
    1/16
  • Zanidatamab
  • Loaded Zanidatamab on AHC2 biosensor, can bind HER2/CD340 Protein, Human (S310Y, HEK293, His, HY-P78680) with an affinity constant of 7.956E-11 M as determined in BLI assay.
  • Immobilized Zanidatamab can bind Human Her2/ERBB2 Protein (ECD, His Tag). The EC50 for this effect is 3.09 ng/mL.
  • half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3