GBM CSCs-IN-1
GBM CSCs-IN-1 (Compound (−)-20), a derivative of rocaglate, is a potent inhibitor of glioblastoma stem cells (GBM CSCs) with an EC50 of 45 nM, functioning by targeting the RNA helicase DDX3. Furthermore, GBM CSCs-IN-1 is also capable of inducing apoptosis.
For research use only. We do not sell to patients.
- CAS No.: 3080542-96-4
- Formula: C28H29BrN2O8S
- Molecular Weight:633.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
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Helicase |
Chemical Information
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CAS No. 3080542-96-4
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Molecular Weight 633.51
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Formula C28H29BrN2O8S
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SMILES
COC1=C2C(O[C@]3(C4=CC=C(Br)C=C4)[C@@]2(O)[C@H](O)[C@H](C(NS(N(C)C)(=O)=O)=O)[C@H]3C5=CC=CC=C5)=CC(OC)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)