SBK3 - SH3 domain binding kinase family member 3 Gene

Also Known as SGK110

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100130827

About SBK3

This gene has 2 transcripts (splice variants), 82 orthologues and 1 paralogue. Biased expression in heart (RPKM 5.3), fat (RPKM 0.8) and 1 other tissue.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

SBK3 Products (1)

mRNA Protein Name
NM_001199824.2 NP_001186753.1 uncharacterized serine/threonine-protein kinase SBK3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SBK3 Protein Structure

Pkinase

Pkinase: Protein kinase domain (43 - 295)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 423 a.a.
Protein Preferred Names Protein Names

uncharacterized serine/threonine-protein kinase SBK3

  • SH3-binding domain kinase family member 3

SBK3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SBK3 P0C264 C1orf105 Homo sapiens O95561
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 C1orf105 Homo sapiens O95561
Y2H Array
32296183
Intra
SBK3 P0C264 POLDIP3 Homo sapiens Q8WUT1
Validated Y2H
32296183
Intra
SBK3 P0C264 POLDIP3 Homo sapiens Q8WUT1
Y2H Array
32296183
Intra
SBK3 P0C264 POLDIP3 Homo sapiens Q8WUT1
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 MBD3L2 Homo sapiens Q8NHZ7
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 MBD3L2 Homo sapiens Q8NHZ7
Y2H Array
32296183
Intra
SBK3 P0C264 MBD3L2 Homo sapiens Q8NHZ7
Validated Y2H
32296183
Intra
SBK3 P0C264 TNNT1 Homo sapiens P13805-3
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 TNNT1 Homo sapiens P13805-3
Validated Y2H
32296183
Intra
SBK3 P0C264 TNNT1 Homo sapiens P13805-3
Y2H Array
32296183
Intra
SBK3 P0C264 SNRNP35 Homo sapiens Q16560-2
Validated Y2H
32296183
Intra
SBK3 P0C264 SNRNP35 Homo sapiens Q16560-2
Y2H Array
32296183
Intra
SBK3 P0C264 SNRNP35 Homo sapiens Q16560-2
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 NOTO Homo sapiens A8MTQ0
Y2H Array
32296183
Intra
SBK3 P0C264 NOTO Homo sapiens A8MTQ0
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 CRY2 Homo sapiens Q49AN0
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 CRY2 Homo sapiens Q49AN0
Y2H Array
32296183
Intra
SBK3 P0C264 CRY2 Homo sapiens Q49AN0
Validated Y2H
32296183
Intra
SBK3 P0C264 EXOSC2 Homo sapiens Q13868
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 EXOSC2 Homo sapiens Q13868
Y2H Array
32296183
Intra
SBK3 P0C264 EXOSC2 Homo sapiens Q13868
Validated Y2H
32296183
Intra
SBK3 P0C264 SMAD3 Homo sapiens P84022
Y2H Array
32296183
Intra
SBK3 P0C264 SMAD3 Homo sapiens P84022
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 SMAD3 Homo sapiens P84022
Validated Y2H
32296183
Intra
SBK3 P0C264 DMAP1 Homo sapiens Q9NPF5
Validated Y2H
32296183
Intra
SBK3 P0C264 DMAP1 Homo sapiens Q9NPF5
Y2H Array
32296183
Intra
SBK3 P0C264 DMAP1 Homo sapiens Q9NPF5
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 AIMP2 Homo sapiens Q13155
Validated Y2H
32296183
Intra
SBK3 P0C264 GATAD2B Homo sapiens Q8WXI9
Y2H Prey Pooling
32296183
Intra
SBK3 P0C264 GATAD2B Homo sapiens Q8WXI9
Validated Y2H
32296183
Intra
SBK3 P0C264 GATAD2B Homo sapiens Q8WXI9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Familial Atrial Fibrillation

  • Atrial Fibrillation, Familial

  • Atfb

  • Atrial Fibrillation Autosomal Dominant

  • Autosomal Dominant Atrial Fibrillation

  • Auricular Fibrillation

  • Atrial Fibrillation

  • Atrial Fibrillation, Familial, 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12468 SBK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SBK3 RGD RGD:1583965
Felis catus SBK3 VGNC VGNC:64888
Macaca mulatta SBK3 VGNC VGNC:82231
Mus musculus SBK3 MGD MGI:2685924
Canis familiaris SBK3 VGNC VGNC:45883
Others SBK3 NCBI