FSBP - fibrinogen silencer binding protein Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100861412

About FSBP

Cytogenetic location: 8q22.1 Genomic coordinates (GRCh38): 8:94,427,716-94,436,944 (from NCBI)

This gene has 2 transcripts (splice variants) and 131 orthologues. Ubiquitous expression in testis (RPKM 1.6), prostate (RPKM 1.4) and 25 other tissues.

Summary

Enables identical protein binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FSBP Products (1)

mRNA Protein Name
NM_001256141.2 NP_001243070.1 fibrinogen silencer-binding protein

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
19060904 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
20531236 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
20531236 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FSBP Protein Structure

Myb_DNA-bind_5

Myb_DNA-bind_5: Myb/SANT-like DNA-binding domain (6 - 85)

  • 0
  • 100
  • 200
  • 299 a.a.
Protein Preferred Names Protein Names

fibrinogen silencer-binding protein

FSBP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FSBP O95073 FLJ13057 Homo sapiens Q53SE7
Validated Y2H
25416956
Intra
FSBP O95073 FLJ13057 Homo sapiens Q53SE7
Y2H Prey Pooling
25416956
Intra
FSBP O95073 q9h614_human Homo sapiens Q9H614
Y2H Prey Pooling
25416956
Intra
FSBP O95073 q9h614_human Homo sapiens Q9H614
Y2H Array
25416956
Intra
FSBP O95073 PRKAA1 Homo sapiens Q13131
Validated Y2H
25416956
Intra
FSBP O95073 ATPAF2 Homo sapiens Q8N5M1
Y2H Array
25416956
Intra
FSBP O95073 SUMO1 Homo sapiens P63165
Y2H Array
25416956
Intra
FSBP O95073 TCEANC Homo sapiens Q8N8B7
Y2H Prey Pooling
25416956
Intra
FSBP O95073 FSBP Homo sapiens O95073
Y2H Array
19060904
Intra
FSBP O95073 ATPAF2 Homo sapiens Q8N5M1
Y2H Prey Pooling
25416956
Intra
FSBP O95073 PRKAA1 Homo sapiens Q13131
Y2H Prey Pooling
25416956
Intra
FSBP O95073 SUMO1 Homo sapiens P63165
Y2H Prey Pooling
25416956
Intra
FSBP O95073 CDC23 Homo sapiens Q9UJX2
Y2H Prey Pooling
25416956
Intra
FSBP O95073 FSBP Homo sapiens O95073
Y2H Array
25416956
Intra
FSBP O95073 ANKRD36BP1 Homo sapiens Q96IX9
Validated Y2H
25416956
Intra
FSBP O95073 ENKD1 Homo sapiens Q9H0I2
Y2H Prey Pooling
25416956
Intra
FSBP O95073 FSBP Homo sapiens O95073
Y2H Pooling
19060904
Intra
FSBP O95073 TCEANC Homo sapiens Q8N8B7
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Microglandular Adenosis

  • Breast Fibrocystic Disease

  • Adenosis - Breast

  • Adenosis Of The Breast

  • Fibrocystic Breast Disease

  • Breast Adenosis

  • Adenosis Of Breast
Postmenopausal Atrophic Vaginitis

  • Atrophic Vaginitis

  • Senile Vaginitis

  • Senile Atrophic Vaginitis

  • Atrophy Of Vagina

  • Vaginal Atrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05117 FSBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FSBP MGD MGI:5301008
Bos taurus FSBP VGNC VGNC:55754
Macaca mulatta FSBP VGNC VGNC:104455
Rattus norvegicus FSBP RGD RGD:7611658
Others FSBP NCBI