AK6 - adenylate kinase 6 Gene

Also Known as CIP; CINAP; AD-004; hCINAP; CGI-137

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 102157402

Summary

This gene encodes a protein that belongs to the adenylate kinase family of Enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Ubiquitous expression in testis (RPKM 18.6), adrenal (RPKM 17.2) and 25 other tissues.

AK6 Products (2)

mRNA Protein Name
NM_001015891.2 NP_001015891.1 adenylate kinase isoenzyme 6 isoform c
NM_016283.5 NP_057367.1 adenylate kinase isoenzyme 6 isoform b

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables adenylate kinase activity IDA
IDA: Inferred from direct assay
15630091 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16079131 GOA
Cellular Component GO Annotation Evidence References Source
located in Cajal body IDA
IDA: Inferred from direct assay
16079131 GOA
NOT located in nucleolus IDA
IDA: Inferred from direct assay
16079131 GOA
located in nucleoplasm IDA
IDA: Inferred from direct assay
16079131 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AK6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
AK6 Q9Y3D8 NDRG1 Homo sapiens Q92597-3
Validated Y2H
25416956
Intra
AK6 Q9Y3D8 NDRG1 Homo sapiens Q92597-3
Y2H Prey Pooling
25416956
Intra
AK6 Q9Y3D8 NDRG1 Homo sapiens Q92597-3
Y2H Array
25416956
Intra
AK6 Q9Y3D8 RPS14 Homo sapiens P62263
Y2H Prey Pooling
25416956
Intra
AK6 Q9Y3D8 RPS14 Homo sapiens P62263
Y2H Array
25416956
Intra
AK6 Q9Y3D8 LAMTOR5 Homo sapiens O43504
Validated Y2H
25416956
Intra
AK6 Q9Y3D8 COIL Homo sapiens P38432
Pull Down
16079131
Intra
AK6 Q9Y3D8 COIL Homo sapiens P38432
IF
16079131
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS00507 AK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00508 AK5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16448 AK6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22080 Ak6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28600 Ak6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown