RFPL3 - ret finger protein like 3 Gene

Also Known as RNF120

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10738

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in innate immune response and regulation of gene expression. Predicted to be located in nucleus. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Biased expression in testis (RPKM 12.5) and prostate (RPKM 0.7).

RFPL3 Products (2)

mRNA Protein Name
NM_001098535.1 NP_001092005.1 ret finger protein-like 3 isoform 1
NM_006604.2 NP_006595.1 ret finger protein-like 3 isoform 2
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RFPL3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RFPL3 O75679 SLAIN1 Homo sapiens Q8ND83 32296183
Intra
RFPL3 O75679 EIF1AX Homo sapiens P47813 32296183
Intra
RFPL3 O75679 EIF1AX Homo sapiens P47813 32296183
Intra
RFPL3 O75679 EIF1AX Homo sapiens P47813 32296183
Intra
RFPL3 O75679 POF1B Homo sapiens Q8WVV4-1 32296183
Intra
RFPL3 O75679 POF1B Homo sapiens Q8WVV4-1 32296183
Intra
RFPL3 O75679 POF1B Homo sapiens Q8WVV4-1 32296183
Intra
RFPL3 O75679 RGP1 Homo sapiens Q92546 32296183
Intra
RFPL3 O75679 C3orf62 Homo sapiens Q6ZUJ4 32296183
Intra
RFPL3 O75679 C3orf62 Homo sapiens Q6ZUJ4 32296183
Intra
RFPL3 O75679 C3orf62 Homo sapiens Q6ZUJ4 32296183
Intra
RFPL3 O75679 PFDN4 Homo sapiens Q9NQP4 32296183
Intra
RFPL3 O75679 PFDN4 Homo sapiens Q9NQP4 32296183
Intra
RFPL3 O75679 PFDN4 Homo sapiens Q9NQP4 32296183
Intra
RFPL3 O75679 HSPB2 Homo sapiens Q16082 32296183
Intra
RFPL3 O75679 HSPB2 Homo sapiens Q16082 32296183
Intra
RFPL3 O75679 HSPB2 Homo sapiens Q16082 32296183
Intra
RFPL3 O75679 HSPB2 Homo sapiens Q16082 32296183
Intra
RFPL3 O75679 LNX1 Homo sapiens Q8TBB1 25416956
Intra
RFPL3 O75679 DDIT4L Homo sapiens Q96D03 32296183
Intra
RFPL3 O75679 DDIT4L Homo sapiens Q96D03 32296183
Intra
RFPL3 O75679 DDIT4L Homo sapiens Q96D03 32296183
Cross: Cross-species interaction Intra: Intraspecies interaction