SNRNP27 - small nuclear ribonucleoprotein U4/U6.U5 subunit 27 Gene

Also Known as 27K; RY1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11017

Summary

This gene encodes a serine/arginine-rich (SR) protein. SR proteins play important roles in pre-mRNA splicing by facilitating the recognition and selection of splice sites. The encoded protein associates with the 25S U4/U6.U5 tri-snRNP, a major component of the U2-type spiceosome. The expression of this gene may be altered in cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1) retrovirus. A pseudogene of this gene is located on the long arm of chromosome 5. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
Ubiquitous expression in brain (RPKM 19.6), adrenal (RPKM 18.4) and 25 other tissues.

SNRNP27 Products (1)

mRNA Protein Name
NM_006857.3 NP_006848.1 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22365833 GOA
Cellular Component GO Annotation Evidence References Source
part of U4/U6 x U5 tri-snRNP complex IPI
IPI: Inferred from physical interaction
30975767 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNRNP27 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SNRNP27 Q8WVK2 CHERP Homo sapiens Q8IWX8
Anti Tag CoIP
22365833
Intra
SNRNP27 Q8WVK2 SRPK2 Homo sapiens P78362
Y2H Array
25416956
Intra
SNRNP27 Q8WVK2 SRPK2 Homo sapiens P78362
Protein Kinase Assay
23602568
Intra
SNRNP27 Q8WVK2 SRPK2 Homo sapiens P78362
Y2H Prey Pooling
25416956
Intra
SNRNP27 Q8WVK2 SRPK2 Homo sapiens P78362
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13497 SNRNP25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown