Arf1 - ADP-ribosylation factor 1 Gene

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 11840

Summary

Enables GTP binding activity and magnesium ion binding activity. Involved in mitotic cleavage furrow ingression. Acts upstream of or within vesicle-mediated transport. Located in Golgi apparatus; cytosol; and sarcomere. Part of protein-containing complex. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; integumental system; and nervous system. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ADP ribosylation factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Arf1 Products (2)

mRNA Protein Name
NM_001130408.2 NP_001123880.1 ADP-ribosylation factor 1
NM_007476.4 NP_031502.1 ADP-ribosylation factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables GTP binding IMP
IMP: Inferred from mutant phenotype
12679809 MGI
enables magnesium ion binding IMP
IMP: Inferred from mutant phenotype
12679809 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12679809 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in mitotic cleavage furrow ingression IGI
IGI: Inferred from genetic interaction
27535433 MGI
acts upstream of or within vesicle-mediated transport IDA
IDA: Inferred from direct assay
14728599 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in Golgi apparatus IDA
IDA: Inferred from direct assay
8947846 MGI
located in cytosol IDA
IDA: Inferred from direct assay
14728599 MGI
located in endomembrane system IDA
IDA: Inferred from direct assay
14728599 MGI
part of protein-containing complex IMP
IMP: Inferred from mutant phenotype
12679809 MGI
located in sarcomere IDA
IDA: Inferred from direct assay
14728599 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP-ribosylation factor 1

Arf1 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Cross
Arf1 P84078 ARHGAP21 Homo sapiens Q5T5U3
Cosedimentation
17347647
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-112473 Grassofermata Inhibitor 99.10% Unkown
HY-173280 Brefeldin A 4-O-nicotinate Inhibitor / Unkown
HY-175290 Arf1-GEFs-IN-1 Inhibitor / Unkown
HY-177269 CHNQD-01269 Inhibitor / Unkown
HY-P10157 ARF(1-22) / Unkown
HY-P10594 Myr-Arf1(2–17) / Unkown
HY-RS00894 ARF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P10658 ARF1 (2-17) Inhibitor / Unkown
HY-RS17736 Arf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24201 Arf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Arf1 NCBI NCBI:375