PRAP1 - proline rich acidic protein 1 Gene

Homo sapiens

Also known as UPA; PRO1195

Gene ID: 118471 | Gene type: protein coding

About PRAP1

Cytogenetic location: 10q26.3 Genomic coordinates (GRCh38): 10:133,347,373-133,352,683 (from NCBI)

This gene has 2 transcripts (splice variants) and 70 orthologues. Biased expression in small intestine (RPKM 388.5), duodenum (RPKM 348.9) and 3 other tissues.

Summary

Predicted to enable triglyceride binding activity. Involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; deactivation of mitotic spindle assembly checkpoint; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PRAP1 Products(2)

mRNA	Protein	Name
NM_001145201.2	NP_001138673.1	proline-rich acidic protein 1 isoform 2 precursor
NM_145202.5	NP_660203.3	proline-rich acidic protein 1 isoform 1 precursor

PRAP1 Protein Structure

PRAP

0
100
151 a.a.

Protein Preferred Names

Protein Names

proline-rich acidic protein 1

epididymis secretory sperm binding protein

Recombinant PRAP1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71004	PRAP1 Protein, Human (HEK293, His)	AAL16670.1 (V21-Q151)	≥95%

Related Diseases

Diseases

Alias

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11050	PRAP1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PRAP1	RGD	RGD:61876
Canis familiaris	PRAP1	VGNC	VGNC:53010
Mus musculus	PRAP1	MGD	MGI:893573
Bos taurus	PRAP1	VGNC	VGNC:55965

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