Bnip3l - BCL2/adenovirus E1B interacting protein 3-like Gene

Also Known as Nix; Nip3L; D14Ertd719e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12177

Summary

Enables identical protein binding activity. Involved in regulation of Autophagy of mitochondrion and regulation of protein targeting to mitochondrion. Acts upstream of or within positive regulation of apoptotic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human BNIP3L (BCL2 interacting protein 3 like). [provided by Alliance of Genome Resources, Apr 2022]

Bnip3l Products (1)

mRNA Protein Name
NM_009761.3 NP_033891.1 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
9867803 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17095503 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
9867803 MGI
involved in regulation of mitophagy IGI
IGI: Inferred from genetic interaction
20200478 MGI
involved in regulation of protein targeting to mitochondrion IGI
IGI: Inferred from genetic interaction
20200478 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
9867803 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

  • BCL2/adenovirus E1B 19 kDa-interacting protein 3-like

  • BCL2/adenovirus E1B 19kDa-interacting protein 3-like

  • NIP3-like protein X

Bnip3l Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Bnip3l Q9Z2F7 MAP1LC3B Homo sapiens Q9GZQ8
NMR
20010802
Cross
Bnip3l Q9Z2F7 MAP1LC3B Homo sapiens Q9GZQ8
Pull Down
20010802
Cross
Bnip3l Q9Z2F7 MAP1LC3B Homo sapiens Q9GZQ8
ITC
20010802
Cross
Bnip3l Q9Z2F7 GABARAPL2 Homo sapiens P60520
Pull Down
20010802
Cross
Bnip3l Q9Z2F7 MAP1LC3A Homo sapiens Q9H492
Pull Down
20010802
Cross
Bnip3l Q9Z2F7 MAP1LC3A Homo sapiens Q9H492
ITC
20010802
Cross
Bnip3l Q9Z2F7 GABARAPL1 Homo sapiens Q9H0R8
IF
20010802
Cross
Bnip3l Q9Z2F7 GABARAPL1 Homo sapiens Q9H0R8
Pull Down
20010802
Intra
Bnip3l Q9Z2F7 Sh3rf1 Mus musculus Q69ZI1
Y2H
17095503
Intra
Bnip3l Q9Z2F7 Sh3rf1 Mus musculus Q69ZI1
Anti Tag CoIP
17095503
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01565 BNIP3L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18697 Bnip3l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25184 Bnip3l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bnip3l NCBI NCBI:665