Cdx1 - caudal type homeobox 1 Gene

Also Known as Cdx; Cdx-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12590

Summary

Enables DNA-binding transcription factor activity. Involved in regulation of somitogenesis. Acts upstream of or within anterior/posterior pattern specification; bone morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; embryo ectoderm; embryo mesenchyme; genitourinary system; and intestine. Orthologous to human CDX1 (caudal type homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Cdx1 Products (1)

mRNA Protein Name
NM_009880.3 NP_034010.3 homeobox protein CDX-1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
22015720 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17158164 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
11784046 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
7585967 MGI
acts upstream of or within bone morphogenesis IGI
IGI: Inferred from genetic interaction
11784046 MGI
acts upstream of or within bone morphogenesis IMP
IMP: Inferred from mutant phenotype
11784046 MGI
acts upstream of or within pattern specification process IMP
IMP: Inferred from mutant phenotype
11959827 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7585967 MGI
involved in regulation of somitogenesis IMP
IMP: Inferred from mutant phenotype
22015720 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein CDX-1

  • caudal type homeo box 1

  • caudal type homeobox transcription factor 1

  • caudal-type homeobox protein 1

Cdx1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Cdx1 P18111 TBP Homo sapiens P20226
Anti Tag CoIP
17158164
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02429 CDX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdx1 NCBI NCBI:1044