PRXL2B - peroxiredoxin like 2B Gene

Also Known as C1orf93; FAM213B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 127281

About PRXL2B

This gene has 15 transcripts (splice variants), 1 gene allele and 83 orthologues. Ubiquitous expression in duodenum (RPKM 15.1), small intestine (RPKM 14.9) and 24 other tissues.

Summary

Predicted to enable antioxidant activity and prostaglandin-F synthase activity. Predicted to be involved in prostaglandin biosynthetic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PRXL2B Products (6)

mRNA Protein Name
NM_001195736.3 NP_001182665.4 prostamide/prostaglandin F synthase isoform a
NM_001195737.3 NP_001182666.4 prostamide/prostaglandin F synthase isoform c
NM_001195738.3 NP_001182667.4 prostamide/prostaglandin F synthase isoform d
NM_001195740.3 NP_001182669.4 prostamide/prostaglandin F synthase isoform e
NM_001195741.3 NP_001182670.4 prostamide/prostaglandin F synthase isoform f
NM_152371.5 NP_689584.5 prostamide/prostaglandin F synthase isoform b

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRXL2B Protein Structure

AhpC-TSA_2

AhpC-TSA_2: AhpC/TSA antioxidant enzyme (84 - 194)

  • 0
  • 100
  • 200
  • 228 a.a.
Protein Preferred Names Protein Names

prostamide/prostaglandin F synthase

  • family with sequence similarity 213 member B

PRXL2B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PRXL2B Q8TBF2 TCP11L1 Homo sapiens Q9NUJ3
Y2H Array
32296183
Intra
PRXL2B Q8TBF2 TCP11L1 Homo sapiens Q9NUJ3
Y2H Prey Pooling
32296183
Intra
PRXL2B Q8TBF2 TCP11L1 Homo sapiens Q9NUJ3
Validated Y2H
32296183
Intra
PRXL2B Q8TBF2 COPS3 Homo sapiens Q9UNS2
Y2H Array
32296183
Intra
PRXL2B Q8TBF2 COPS3 Homo sapiens Q9UNS2
Y2H Prey Pooling
32296183
Intra
PRXL2B Q8TBF2 COPS3 Homo sapiens Q9UNS2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11266 PRXL2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PRXL2B RGD RGD:1308251
Felis catus PRXL2B VGNC VGNC:64407
Bos taurus PRXL2B VGNC VGNC:28792
Canis familiaris PRXL2B VGNC VGNC:40661
Macaca mulatta PRXL2B VGNC VGNC:76332
Mus musculus PRXL2B MGD MGI:1913719
Others PRXL2B NCBI