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TCP11L1 - t-complex 11 like 1 Gene

Also Known as dJ85M6.3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 55346

About TCP11L1

This gene has 11 transcripts (splice variants), 205 orthologues and 4 paralogues. Ubiquitous expression in brain (RPKM 7.3), small intestine (RPKM 3.3) and 25 other tissues.

Summary

Predicted to be involved in signal transduction. Located in microtubule. [provided by Alliance of Genome Resources, Apr 2022]

TCP11L1 Products (2)

mRNA	Protein	Name
NM_001145541.1	NP_001139013.1	T-complex protein 11-like protein 1
NM_018393.4	NP_060863.3	T-complex protein 11-like protein 1

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in microtubule	IDA IDA: Inferred from direct assay	21525035	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TCP11L1 Protein Structure

Tcp11

0
100
200
300
400
509 a.a.

Protein Preferred Names	Protein Names
T-complex protein 11-like protein 1	t-complex 11, testis-specific-like 1

TCP11L1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	TCP11L1	Q9NUJ3	REL	Homo sapiens	Q04864-2	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	REL	Homo sapiens	Q04864-2	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	LHX2	Homo sapiens	P50458	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	LHX2	Homo sapiens	P50458	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	CNOT7	Homo sapiens	Q9UIV1	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	CNOT7	Homo sapiens	Q9UIV1	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	CNOT7	Homo sapiens	Q9UIV1	Validated Y2H	32296183
Intra	TCP11L1	Q9NUJ3	TSNAX	Homo sapiens	Q99598	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	TSNAX	Homo sapiens	Q99598	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	PLEKHS1	Homo sapiens	Q5SXH7-1	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	PLEKHS1	Homo sapiens	Q5SXH7-1	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	VPS52	Homo sapiens	Q8N1B4	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	VPS52	Homo sapiens	Q8N1B4	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	MEOX1	Homo sapiens	P50221	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	MEOX1	Homo sapiens	P50221	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	PSMD4	Homo sapiens	P55036	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	PSMD4	Homo sapiens	P55036	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	ERCC6L2	Homo sapiens	Q5T890	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	IPO4	Homo sapiens	Q8TEX9	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	IPO4	Homo sapiens	Q8TEX9	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	SNW1	Homo sapiens	Q13573	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	SNW1	Homo sapiens	Q13573	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	PRXL2B	Homo sapiens	Q8TBF2	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	PRXL2B	Homo sapiens	Q8TBF2	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	HMG20A	Homo sapiens	Q9NP66	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	HMG20A	Homo sapiens	Q9NP66	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	SDCBP2	Homo sapiens	Q9H190	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	SDCBP2	Homo sapiens	Q9H190	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	PAX6	Homo sapiens	P26367	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	PAX6	Homo sapiens	P26367	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	WWTR1	Homo sapiens	Q9GZV5	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	WWTR1	Homo sapiens	Q9GZV5	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	MAGEA12	Homo sapiens	P43365	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	MAGEA12	Homo sapiens	P43365	Y2H Prey Pooling	32296183
Intra	TCP11L1	Q9NUJ3	TRIM21	Homo sapiens	P19474	Y2H Array	32296183
Intra	TCP11L1	Q9NUJ3	TRIM21	Homo sapiens	P19474	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Cryptorchidism, Unilateral Or Bilateral	Cryptorchidism Undescended Testicle Undescended Testis Cryptorchism Undescended Testicles CRYPTO Impaired Testicular Descent Cryptosporidiosis Retained Testis Unilateral Cryptorchidism Unilateral Undescended Testis Nondescent Unilateral Testicle Unilateral Cryptorchism Ectopic Testis, Unilateral Bilateral Cryptorchidism Bilateral Cryptorchism Bilateral Nondescent Testicle Bilateral Undescended Testes Bilateral Ectopic Testes

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14323	TCP11L1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TCP11L1	MGD	MGI:2444263
Bos taurus	TCP11L1	VGNC	VGNC:35703
Felis catus	TCP11L1	VGNC	VGNC:66036
Macaca mulatta	TCP11L1	VGNC	VGNC:79527
Rattus norvegicus	TCP11L1	RGD	RGD:1562313
Canis familiaris	TCP11L1	VGNC	VGNC:47209
Others	TCP11L1	NCBI