Clk4 - CDC like kinase 4 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12750

Summary

Enables protein serine/threonine kinase activity and protein tyrosine kinase activity. Acts upstream of or within peptidyl-tyrosine phosphorylation and protein autophosphorylation. Located in nucleus. Is expressed in several structures, including endocrine gland; gonad; hemolymphoid system gland; liver; and tongue. Orthologous to human CLK4 (CDC like kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Clk4 Products (16)

mRNA Protein Name
NM_001304744.1 NP_001291673.1 dual specificity protein kinase CLK4 isoform 2
NM_001362535.1 NP_001349464.1 dual specificity protein kinase CLK4 isoform 3
NM_001362536.1 NP_001349465.1 dual specificity protein kinase CLK4 isoform 4
NM_001362538.1 NP_001349467.1 dual specificity protein kinase CLK4 isoform 4
NM_001362539.1 NP_001349468.1 dual specificity protein kinase CLK4 isoform 2
NM_001362540.1 NP_001349469.1 dual specificity protein kinase CLK4 isoform 2
NM_001362541.1 NP_001349470.1 dual specificity protein kinase CLK4 isoform 2
NM_007714.6 NP_031740.1 dual specificity protein kinase CLK4 isoform 1
NM_001304744.1 NP_001291673.1 dual specificity protein kinase CLK4 isoform 2
NM_001362535.1 NP_001349464.1 dual specificity protein kinase CLK4 isoform 3
NM_001362536.1 NP_001349465.1 dual specificity protein kinase CLK4 isoform 4
NM_001362538.1 NP_001349467.1 dual specificity protein kinase CLK4 isoform 4
NM_001362539.1 NP_001349468.1 dual specificity protein kinase CLK4 isoform 2
NM_001362540.1 NP_001349469.1 dual specificity protein kinase CLK4 isoform 2
NM_001362541.1 NP_001349470.1 dual specificity protein kinase CLK4 isoform 2
NM_007714.6 NP_031740.1 dual specificity protein kinase CLK4 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
9307018 MGI
enables protein tyrosine kinase activity IDA
IDA: Inferred from direct assay
9307018 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
9307018 MGI
acts upstream of or within protein autophosphorylation IDA
IDA: Inferred from direct assay
9307018 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
9307018 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual specificity protein kinase CLK4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (24)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15338 TG003 Inhibitor 99.57% Unkown
HY-112296 T025 99.64% Unkown
HY-15951 ML167 Inhibitor 98.62% Unkown
HY-155723 Leucettinib-92 Inhibitor 98.54% Unkown
HY-153708 SGC-CLK-1 Inhibitor 99.12% Unkown
HY-123600 SRI-29329 Inhibitor 99.14% Unkown
HY-125290 MU1210 Inhibitor 99.50% Unkown
HY-111379 EHT 5372 Inhibitor 98.12% Unkown
HY-149262 CLK1-IN-3 98.54% Unkown
HY-12828A KH-CB20 Inhibitor 99.80% Unkown
HY-131978 DB18 Inhibitor 99.15% Unkown
HY-15338A (E/Z)-TG003 Inhibitor 99.9% Unkown
HY-183068 AP4-43 Inhibitor / Unkown
HY-125202 KuWal151 Inhibitor / Unkown
HY-146335 CLK1/4-IN-1 Inhibitor / Unkown
HY-176884 CDD-2110 Inhibitor / Unkown
HY-176885 CDD-2211 Inhibitor / Unkown
HY-176885A CDD-2212 Inhibitor / Unkown
HY-182957 MNK/PIM-IN-2 / Unkown
HY-183831 GPS167 / Unkown
HY-RS02819 CLK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W409652 CLK1/4-IN-2 Inhibitor / Unkown
HY-RS17487 Clk4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23945 Clk4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clk4 NCBI NCBI:57396