MPP7 - MAGUK p55 scaffold protein 7 Gene

Homo sapiens

Gene ID: 143098 | Gene type: protein coding

About MPP7

Cytogenetic location: 10p12.1 Genomic coordinates (GRCh38): 10:28,050,993-28,335,203 (from NCBI)

This gene has 9 transcripts (splice variants), 225 orthologues and 7 paralogues. Ubiquitous expression in esophagus (RPKM 17.1), skin (RPKM 11.1) and 24 other tissues.

Summary

The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in this gene are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

MPP7 Products(2)

mRNA	Protein	Name
NM_001318170.2	NP_001305099.1	MAGUK p55 subfamily member 7
NM_173496.5	NP_775767.2	MAGUK p55 subfamily member 7

MPP7 Protein Structure

L27

PDZ

SH3_2

Guanylate_kin

0
100
200
300
400
500
576 a.a.

Protein Preferred Names

Protein Names

MAGUK p55 subfamily member 7

membrane palmitoylated protein 7

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08626	MPP7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MPP7	MGD	MGI:1922989
Macaca mulatta	MPP7	VGNC	VGNC:74835
Bos taurus	MPP7	VGNC	VGNC:31586
Rattus norvegicus	MPP7	RGD	RGD:1305675
Canis familiaris	MPP7	VGNC	VGNC:49833
Felis catus	MPP7	VGNC	VGNC:97517