E2F7 - E2F transcription factor 7 Gene

Homo sapiens

Gene ID: 144455 | Gene type: protein coding

About E2F7

Cytogenetic location: 12q21.2 Genomic coordinates (GRCh38): 12:77,021,251-77,065,569 (from NCBI)

This gene has 7 transcripts (splice variants), 211 orthologues and 7 paralogues. Broad expression in testis (RPKM 1.6), bone marrow (RPKM 1.5) and 16 other tissues.

Summary

E2F transcription factors, such as E2F7, play an essential role in the regulation of cell cycle progression (Di Stefano et al., 2003 [PubMed 14633988]).[supplied by OMIM, May 2008]

E2F7 Products(1)

mRNA	Protein	Name
NM_203394.3	NP_976328.2	transcription factor E2F7

E2F7 Protein Structure

E2F_TDP

0
200
400
600
800
911 a.a.

Protein Preferred Names

Protein Names

transcription factor E2F7

E2F-7

Related Diseases

Diseases

Alias

Retinal Cancer

Malignant Neoplasm Of Retina	Retinal Neoplasms
Malignant Retinal Neoplasm	Malignant Tumor Of Retina
Neoplasm Of Retina	Retinal Tumor
Retinal Neoplasm	Cancer Of The Retina
Malignant Retinal Tumour	Malignant Tumour Of Retina
Primary Malignant Neoplasm Of Retina

Bilateral Retinoblastoma

Soft Palate Cancer

Malignant Tumor Of Soft Palate	Malignant Tumor Of The Soft Palate
Palate Cancer Soft Palate

Familial Retinoblastoma

Hereditary Retinoblastoma

Retinoblastoma

Ocular Cancer

Eye Neoplasm	Eye Carcinoma
Eye Cancer	Eye Neoplasms
Malignant Eye Neoplasm	Neoplasm Of Eye
Neoplasm Of Eye Proper	Ocular Tumor
Carcinoma Of Eye	Ocular Carcinoma
Malignant Tumor Of Eye

Retinal Disease

Retinal Diseases	Retinal Disorder
Retinal Disorders

Eye Disease

Eye Diseases	Abnormality Of The Eye
Toxoplasma Oculopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04116	E2F7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	E2F7	MGD	MGI:1289147
Canis familiaris	E2F7	VGNC	VGNC:40169
Felis catus	E2F7	VGNC	VGNC:61698
Bos taurus	E2F7	VGNC	VGNC:28291
Macaca mulatta	E2F7	VGNC	VGNC:71891
Rattus norvegicus	E2F7	RGD	RGD:1310258