HSFY2 - heat shock transcription factor Y-linked 2 Gene

Also Known as HSFY; HSF2L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 159119

Summary

This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Restricted expression toward testis (RPKM 13.8).

HSFY2 Products (2)

mRNA Protein Name
NM_001001877.2 NP_001001877.1 heat shock transcription factor, Y-linked isoform 2
NM_153716.2 NP_714927.1 heat shock transcription factor, Y-linked isoform 1
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24722188 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HSFY2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HSFY1 Q96LI6 RBM47 Homo sapiens B7ZLP7 25416956
Intra
HSFY1 Q96LI6 GCM2 Homo sapiens O75603 25416956
Intra
HSFY1 Q96LI6 GCM2 Homo sapiens O75603 29892012
Intra
HSFY1 Q96LI6 GCM2 Homo sapiens O75603 31515488
Intra
HSFY1 Q96LI6 JPH3 Homo sapiens Q8WXH2 32814053
Intra
HSFY1 Q96LI6 JPH3 Homo sapiens Q8WXH2 32814053
Intra
HSFY1 Q96LI6 JPH3 Homo sapiens Q8WXH2 32814053
Intra
HSFY1 Q96LI6 TOX2 Homo sapiens Q96NM4-3 32296183
Intra
HSFY1 Q96LI6 TOX2 Homo sapiens Q96NM4-3 32296183
Intra
HSFY1 Q96LI6 TOX2 Homo sapiens Q96NM4-3 32296183
Intra
HSFY1 Q96LI6 TBX6 Homo sapiens O95947 25416956
Intra
HSFY1 Q96LI6 HNRNPF Homo sapiens P52597 25416956
Intra
HSFY1 Q96LI6 VIM Homo sapiens P08670 32814053
Intra
HSFY1 Q96LI6 VIM Homo sapiens P08670 32814053
Intra
HSFY1 Q96LI6 VIM Homo sapiens P08670 32814053
Intra
HSFY1 Q96LI6 UBE2K Homo sapiens P61086 32814053
Intra
HSFY1 Q96LI6 UBE2K Homo sapiens P61086 32814053
Intra
HSFY1 Q96LI6 UBE2K Homo sapiens P61086 32814053
Intra
HSFY1 Q96LI6 OTUD7B Homo sapiens Q6GQQ9 32296183
Intra
HSFY1 Q96LI6 OTUD7B Homo sapiens Q6GQQ9 32296183
Intra
HSFY1 Q96LI6 SOX15 Homo sapiens O60248 25416956
Intra
HSFY1 Q96LI6 SOX15 Homo sapiens O60248 25416956
Intra
HSFY1 Q96LI6 SOX15 Homo sapiens O60248 25416956
Intra
HSFY1 Q96LI6 PECAM1 Homo sapiens P16284 32814053
Intra
HSFY1 Q96LI6 PECAM1 Homo sapiens P16284 32814053
Intra
HSFY1 Q96LI6 PECAM1 Homo sapiens P16284 32814053
Intra
HSFY1 Q96LI6 DAZAP2 Homo sapiens Q15038 32296183
Intra
HSFY1 Q96LI6 DAZAP2 Homo sapiens Q15038 32296183
Intra
HSFY1 Q96LI6 BPIFA1 Homo sapiens Q9NP55 32296183
Intra
HSFY1 Q96LI6 BPIFA1 Homo sapiens Q9NP55 32296183
Intra
HSFY1 Q96LI6 BPIFA1 Homo sapiens Q9NP55 32296183
Cross: Cross-species interaction Intra: Intraspecies interaction