Ikzf2 - IKAROS family zinc finger 2 Gene

Also Known as Helios; Zfpn1a2; Znfn1a2; A730095J18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22779

Summary

Enables identical protein binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in early conceptus and genitourinary system. Orthologous to human IKZF2 (IKAROS family zinc finger 2). [provided by Alliance of Genome Resources, Apr 2022]

Ikzf2 Products (8)

mRNA Protein Name
NM_001402850.1 NP_001389779.1 zinc finger protein Helios isoform 1
NM_001402852.1 NP_001389781.1 zinc finger protein Helios isoform 2
NM_001402853.1 NP_001389782.1 zinc finger protein Helios isoform 2
NM_001402854.1 NP_001389783.1 zinc finger protein Helios isoform 2
NM_001402855.1 NP_001389784.1 zinc finger protein Helios isoform 3
NM_001402856.1 NP_001389785.1 zinc finger protein Helios isoform 4
NM_001402857.1 NP_001389786.1 zinc finger protein Helios isoform 2
NM_011770.5 NP_035900.2 zinc finger protein Helios isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
9560339 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9560339 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
9560339 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein Helios

  • ikaros family zinc finger protein 2

  • zinc finger protein, subfamily 1A, 2 (Helios)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-173630 BMS-986449 Inhibitor / Phase 2
HY-182467 BMS-986482 Degrader / Phase 2
HY-145776 ALV1 Inhibitor 98.62% Phase 1

Pre-clinical Phase

Bioactive Molecules (24)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-144998 NVP-DKY709 Inhibitor 99.66% Unkown
HY-157334 DEG-77 99.03% Unkown
HY-W1135319 SB-405483 99.33% Unkown
HY-159647 PLX-4545 96.76% Unkown
HY-159647A (S,S)-PLX-4545 Degrader / Unkown
HY-172931 DEG-35 Degrader 98.88% Unkown
HY-168615 MGD-28 Degrader 99.73% Unkown
HY-173630A (Rac)-BMS-986449 Inhibitor 99.05% Unkown
HY-172930 PVTX-405 97.07% Unkown
HY-159647B (1S,2S,3R)-PLX-4545 Degrader 91.78% Unkown
HY-168614 MGD-4 Degrader / Unkown
HY-182467A BMS-986482 acetate / Unkown
HY-RS06666 IKZF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-172882 IKZF2-degrader 1 Degrader / Unkown
HY-172930B (R)-PVTX-405 Degrader / Unkown
HY-177754 IKZF2-degrader 3 Degrader / Unkown
HY-182799 IBA-12 Degrader / Unkown
HY-182807 CRBN ligand-899 / Unkown
HY-182808 E3 Ligase Ligand-linker Conjugate 230 / Unkown
HY-182945 IKZF2-degrader 5 / Unkown
HY-W1128213 IKZF2-degrader 2 Degrader / Unkown
HY-185300 IKZF2-degrader 4 Degrader / Unkown
HY-RS20037 Ikzf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26540 Ikzf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ikzf2 NCBI NCBI:22807