U2SURP - U2 snRNP associated SURP domain containing Gene

Also Known as SR140; fSAPa

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23350

About U2SURP

Cytogenetic location: 3q23 Genomic coordinates (GRCh38): 3:143,001,570-143,060,725 (from NCBI)

This gene has 17 transcripts (splice variants) and 212 orthologues. Ubiquitous expression in bone marrow (RPKM 18.6), lymph node (RPKM 15.0) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in RNA processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

U2SURP Products (4)

mRNA Protein Name
NM_001080415.2 NP_001073884.1 U2 snRNP-associated SURP motif-containing protein isoform 1
NM_001320219.2 NP_001307148.1 U2 snRNP-associated SURP motif-containing protein isoform 2
NM_001320220.2 NP_001307149.1 U2 snRNP-associated SURP motif-containing protein isoform 3
NM_001320222.2 NP_001307151.1 U2 snRNP-associated SURP motif-containing protein isoform 4

U2SURP Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (276 - 348)

Surp

Surp: Surp module (428 - 480)

cwf21

cwf21: cwf21 domain (837 - 885)

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  • 1029 a.a.
Protein Preferred Names Protein Names

U2 snRNP-associated SURP motif-containing protein

  • 140 kDa Ser/Arg-rich domain protein

U2SURP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
U2SURP O15042 CHERP Homo sapiens Q8IWX8
Anti Tag CoIP
35271311
Intra
U2SURP O15042 CHERP Homo sapiens Q8IWX8
Crosslink
30021884
Intra
U2SURP O15042 RBM5 Homo sapiens P52756
Anti Tag CoIP
22365833
Intra
U2SURP O15042 RBM5 Homo sapiens P52756
Y2H
22365833
Cross: Cross-species interaction Intra: Intraspecies interaction

U2SURP Antibodies

Cat. No. Product Name Application Reactivity
HY-P810094 SR140 Antibody (YA9438) WB, ICC/IF, IF-Tissue, IP, ELISA human, mouse, rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15315 U2SURP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21969 U2surp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28486 U2surp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus U2SURP RGD RGD:1307882
Felis catus U2SURP VGNC VGNC:66742
Macaca mulatta U2SURP VGNC VGNC:79889
Bos taurus U2SURP VGNC VGNC:36557
Mus musculus U2SURP MGD MGI:1915208
Canis familiaris U2SURP VGNC VGNC:48033
Others U2SURP NCBI