2. Gene
  3. Il3 - interleukin 3 Gene

Il3 - interleukin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 24495 | Gene type: protein coding

About Il3

Primary_assembly 10: 38,405,716-38,408,066 reverse strand.mRatBN7.2:CM026983.1

This gene has 1 transcript (splice variant), 42 orthologues and is associated with 29 phenotypes. Low expression observed in reference dataset.

Summary

Enables cytokine activity and interleukin-3 receptor binding activity. Involved in several processes, including hemopoiesis; positive regulation of cell population proliferation; and regulation of cell growth. Located in extracellular space. Used to study osteosarcoma. Biomarker of prostatic hypertrophy and pyelonephritis. Human ortholog(s) of this gene implicated in Graves' disease; asthma; and rheumatoid arthritis. Orthologous to human IL3 (interleukin 3). [provided by Alliance of Genome Resources, Apr 2022]

Il3 Products(1)

mRNA Protein Name
NM_031513.2 NP_113701.2 interleukin-3 precursor

Il3 Protein Structure

IL3

IL3: pfam02059 (33 - 139)

  • 0
  • 100
  • 166 a.a.
Protein Preferred Names Protein Names

interleukin-3

IL-3

MCGF

P-cell-stimulating factor

hematopoietic growth factor

mast cell growth factor

multipotential colony-stimulating factor

Recombinant Il3 Proteins

Cat. No. Product Name Accession Purity
HY-P7375 IL-3 Protein, Rat (CHO, His) P97688 (I27-C169) ≥95%
HY-P7376 IL-3 beta Protein, Rat P97688 ≥95%
HY-P73208 IL-3 Protein, Rat (sf9, His) P97688 (I27-C169) ≥95%

Related Agents

Approval
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1402 Hydrocortisone hemisuccinate 99.76% Unkown
HY-B1155 Hydrocortisone phosphate / Unkown
HY-B1402B Hydrocortisone hemisuccinate sodium Inhibitor / Unkown
HY-B1402R Hydrocortisone hemisuccinate (Standard) / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99536 Tagraxofusp Inhibitor / Unkown
Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99395 Talacotuzumab Inhibitor 95.00% Phase 3
HY-P99234 Pivekimab Inhibitor 96.12% Phase 1
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-155951 JAK3-IN-14 Inhibitor 99.32% Unkown
HY-P1111 Lyn peptide inhibitor Inhibitor / Unkown
HY-P1111A Lyn peptide inhibitor TFA Inhibitor / Unkown
HY-RS06751 IL3 Human Pre-designed siRNA Set A / Unkown
HY-RS06752 Il3 Mouse Pre-designed siRNA Set A / Unkown
HY-RS06753 Il3 Rat Pre-designed siRNA Set A / Unkown
HY-RS06764 IL3RA Human Pre-designed siRNA Set A / Unkown
HY-14271 Acreozast / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il3 NCBI NCBI:3562
Canis familiaris Il3 NCBI NCBI:481497
Macaca fascicularis Il3 NCBI NCBI:102118362
Mus musculus Il3 NCBI NCBI:16187
Macaca mulatta Il3 NCBI NCBI:706946