CDK4/6-IN-23
CDK4/6-IN-23 (Compound 42) is a potent and selective CDK4/6 inhibitor, with an IC50 of 11 nM for CDK6. CDK4/6-IN-23 can significantly activate immune cells and promote the production of IL-3. CDK4/6-IN-23 has dual myeloprotective and immunomodulatory effects in 5-FU (HY-90006) chemotherapy mice.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C32H34FN7O4
- Molecular Weight:599.66
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
|
CDK6 11 nM (IC50) |
CDK4 |
Chemical Information
-
Molecular Weight 599.66
-
Formel C32H34FN7O4
-
SMILES
CC(N1CCC2(CC(C3=CC=C(C=C3O2)C4=C(C=NC(NC5=CC=C(C=N5)N6CCN(CC6)C(C7CC7)=O)=N4)F)=O)CC1)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)