CDK4/6-IN-23
CDK4/6-IN-23 (Compound 42) is a potent and selective CDK4/6 inhibitor, with an IC50 of 11 nM for CDK6. CDK4/6-IN-23 can significantly activate immune cells and promote the production of IL-3. CDK4/6-IN-23 has dual myeloprotective and immunomodulatory effects in 5-FU (HY-90006) chemotherapy mice.
For research use only. We do not sell to patients.
- Formula: C32H34FN7O4
- Molecular Weight:599.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK6 11 nM (IC50) |
CDK4 |
Chemical Information
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Molecular Weight 599.66
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Formula C32H34FN7O4
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SMILES
CC(N1CCC2(CC(C3=CC=C(C=C3O2)C4=C(C=NC(NC5=CC=C(C=N5)N6CCN(CC6)C(C7CC7)=O)=N4)F)=O)CC1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)