DEFB121 - defensin beta 121 Gene
Also Known as DEFB21; ESC42RELC
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 245934
Summary
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are Antimicrobial Peptides that protect tissues and organs from Infection by a variety of Microorganisms. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Restricted expression toward testis (RPKM 1.3).
DEFB121 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001011878.3 | NP_001011878.1 | beta-defensin 121 isoform 1 precursor |
| NM_001171832.2 | NP_001165303.1 | beta-defensin 121 isoform 2 |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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DEFB121 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
DEFB121 | Q5J5C9 | LRRC25 | Homo sapiens | Q8N386 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | LRRC25 | Homo sapiens | Q8N386 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | LRRC25 | Homo sapiens | Q8N386 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | CLEC2D | Homo sapiens | Q9UHP7-3 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | CLEC2D | Homo sapiens | Q9UHP7-3 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | CLEC2D | Homo sapiens | Q9UHP7-3 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | SSMEM1 | Homo sapiens | Q8WWF3 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | SSMEM1 | Homo sapiens | Q8WWF3 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | SSMEM1 | Homo sapiens | Q8WWF3 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | IL27RA | Homo sapiens | Q6UWB1 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | IL27RA | Homo sapiens | Q6UWB1 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | IL27RA | Homo sapiens | Q6UWB1 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | LAYN | Homo sapiens | Q6UX15-2 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | LAYN | Homo sapiens | Q6UX15-2 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | LAYN | Homo sapiens | Q6UX15-2 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | NECTIN4 | Homo sapiens | Q96NY8 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | NECTIN4 | Homo sapiens | Q96NY8 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | NECTIN4 | Homo sapiens | Q96NY8 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | CD40 | Homo sapiens | P25942 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | CD40 | Homo sapiens | P25942 | 32296183 | |
|
Intra
|
DEFB121 | Q5J5C9 | SYNE4 | Homo sapiens | Q8N205 | 25416956 |
Cross: Cross-species interaction
Intra: Intraspecies interaction