Ppp1cb - protein phosphatase 1 catalytic subunit beta Gene

Also Known as PP1B; PP1beta

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25594

Summary

Enables phosphoprotein Phosphatase activity. Involved in protein dephosphorylation; regulation of glycogen biosynthetic process; and regulation of glycogen catabolic process. Located in glycogen granule. Part of protein Phosphatase type 1 complex. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 2. Orthologous to human PPP1CB (protein Phosphatase 1 catalytic subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1cb Products (1)

mRNA Protein Name
NM_013065.2 NP_037197.1 serine/threonine-protein phosphatase PP1-beta catalytic subunit

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphoprotein phosphatase activity IDA
IDA: Inferred from direct assay
7720853 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
7649987 RGD
Biological Process GO Annotation Evidence References Source
involved in protein dephosphorylation IDA
IDA: Inferred from direct assay
7720853 RGD
involved in regulation of glycogen biosynthetic process IDA
IDA: Inferred from direct assay
7720853 RGD
involved in regulation of glycogen catabolic process IDA
IDA: Inferred from direct assay
7720853 RGD
Cellular Component GO Annotation Evidence References Source
located in glycogen granule IDA
IDA: Inferred from direct assay
7720853 RGD
part of protein phosphatase type 1 complex IDA
IDA: Inferred from direct assay
7720853 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase PP1-beta catalytic subunit

  • PP-1B

  • protein phosphatase 1, catalytic subunit, beta isozyme

  • protein phosphatase-1a

Ppp1cb Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Ppp1cb P62142 Ppp1r9a Rattus norvegicus O35867
Anti Tag CoIP
18216290
Intra
Ppp1cb P62142 Rpl5 Rattus norvegicus P09895
Y2H
7649987
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10974 PPP1CB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp1cb NCBI NCBI:5500