PGLS - 6-phosphogluconolactonase Gene

Also Known as 6PGL; HEL-S-304

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25796

About PGLS

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:17,511,649-17,521,288 (from NCBI)

This gene has 6 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in spleen (RPKM 10.2), colon (RPKM 9.1) and 25 other tissues.

Summary

Enables 6-phosphogluconolactonase activity. Involved in pentose-phosphate shunt. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PGLS Products (1)

mRNA Protein Name
NM_012088.3 NP_036220.1 6-phosphogluconolactonase

PGLS Protein Structure

Glucosamine_iso

Glucosamine_iso: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase (20 - 216)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

6-phosphogluconolactonase

  • epididymis secretory protein Li 304

PGLS Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PGLS O95336 BLMH Homo sapiens Q13867
Y2H Array
32296183
Intra
PGLS O95336 BLMH Homo sapiens Q13867
Validated Y2H
32296183
Intra
PGLS O95336 TERF2IP Homo sapiens Q9NYB0
BiFC
21044950
Intra
PGLS O95336 TERF2IP Homo sapiens Q9NYB0
Pull Down
21044950
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123148 IMB-808 Agonist 99.84% Unkown
HY-139691 SR15006 Inhibitor 99.90% Unkown
HY-113736 Glycyllysine 95.34% Unkown
HY-RS10386 PGLS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22277 Pgls Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28800 Pgls Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PGLS RGD RGD:1307001
Macaca mulatta PGLS VGNC VGNC:75967
Canis familiaris PGLS VGNC VGNC:44460
Felis catus PGLS VGNC VGNC:80652
Bos taurus PGLS VGNC VGNC:32790
Mus musculus PGLS MGD MGI:1913421
Others PGLS NCBI