PGLS - 6-phosphogluconolactonase Gene

Homo sapiens

Also known as 6PGL; HEL-S-304

Gene ID: 25796 | Gene type: protein coding

About PGLS

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:17,511,649-17,521,288 (from NCBI)

This gene has 6 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in spleen (RPKM 10.2), colon (RPKM 9.1) and 25 other tissues.

Summary

Enables 6-phosphogluconolactonase activity. Involved in pentose-phosphate shunt. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PGLS Products(1)

mRNA	Protein	Name
NM_012088.3	NP_036220.1	6-phosphogluconolactonase

PGLS Protein Structure

Glucosamine_iso

0
100
200
258 a.a.

Protein Preferred Names

Protein Names

6-phosphogluconolactonase

epididymis secretory protein Li 304

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-123148	IMB-808	Agonist	99.85%	Unkown
HY-139691	SR15006	Inhibitor	99.95%	Unkown
HY-113736	Glycyllysine		/	Unkown
HY-RS10386	PGLS Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PGLS	RGD	RGD:1307001
Macaca mulatta	PGLS	VGNC	VGNC:75967
Canis familiaris	PGLS	VGNC	VGNC:44460
Felis catus	PGLS	VGNC	VGNC:80652
Bos taurus	PGLS	VGNC	VGNC:32790
Mus musculus	PGLS	MGD	MGI:1913421

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