MPC2 - mitochondrial pyruvate carrier 2 Gene

Homo sapiens

Also known as BRP44; SLC54A2

Gene ID: 25874 | Gene type: protein coding

About MPC2

Cytogenetic location: 1q24.2 Genomic coordinates (GRCh38): 1:167,916,675-167,937,072 (from NCBI)

This gene has 3 transcripts (splice variants), 257 orthologues and 2 paralogues. Broad expression in kidney (RPKM 34.8), liver (RPKM 32.8) and 25 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to act upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate and positive regulation of Insulin secretion involved in cellular response to glucose stimulus. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

MPC2 Products(2)

mRNA	Protein	Name
NM_001143674.4	NP_001137146.1	mitochondrial pyruvate carrier 2
NM_015415.3	NP_056230.1	mitochondrial pyruvate carrier 2

MPC2 Protein Structure

MPC

0
100
127 a.a.

Protein Preferred Names

Protein Names

mitochondrial pyruvate carrier 2

brain protein 44

Related Diseases

Diseases

Alias

Mitochondrial Pyruvate Carrier Deficiency

MPYCD

Colon Mucinous Adenocarcinoma

Colonic Mucinous Adenocarcinoma

Mucinous Adenocarcinoma Of The Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08607	MPC2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MPC2	VGNC	VGNC:107897
Mus musculus	MPC2	MGD	MGI:1917706
Bos taurus	MPC2	VGNC	VGNC:31570
Macaca mulatta	MPC2	VGNC	VGNC:97793
Canis familiaris	MPC2	VGNC	VGNC:43330
Rattus norvegicus	MPC2	RGD	RGD:1563422