Lypla2 - lysophospholipase 2 Gene

Also Known as LysoII

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26394

Summary

Enables palmitoyl-(protein) hydrolase activity. Involved in prostaglandin catabolic process and protein depalmitoylation. Located in Golgi stack. Is expressed in several structures, including alimentary system; eye; integumental system; nervous system; and urinary system. Orthologous to human LYPLA2 (lysophospholipase 2). [provided by Alliance of Genome Resources, Apr 2022]

Lypla2 Products (1)

mRNA Protein Name
NM_011942.1 NP_036072.1 acyl-protein thioesterase 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables palmitoyl-(protein) hydrolase activity IDA
IDA: Inferred from direct assay
27307232 MGI
Biological Process GO Annotation Evidence References Source
involved in prostaglandin catabolic process IDA
IDA: Inferred from direct assay
25301951 MGI
involved in protein depalmitoylation IDA
IDA: Inferred from direct assay
27307232 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi stack IDA
IDA: Inferred from direct assay
27307232 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
27307232 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyl-protein thioesterase 2

  • APT-2

  • LPL-II

  • lysoPLA II

  • lysophospholipase II

  • mLyso II

  • palmitoyl-protein hydrolase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100736 ML348 Inhibitor 99.97% Unkown
HY-100737 ML349 Inhibitor 99.47% Unkown
HY-128035 ML-211 Inhibitor 99.42% Unkown
HY-129121 ML-​226 Inhibitor 98.76% Unkown
HY-120126 ML378 Inhibitor / Unkown
HY-RS07922 LYPLA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18712 Lypla2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25199 Lypla2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lypla2 NCBI NCBI:11313