ZNF777 - zinc finger protein 777 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 27153

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription; negative regulation of cell population proliferation; and protein heterooligomerization. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in ovary (RPKM 4.5), brain (RPKM 4.0) and 25 other tissues.

ZNF777 Products (1)

mRNA Protein Name
NM_015694.3 NP_056509.2 zinc finger protein 777

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
31856708 GOA
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
25560148 GOA
involved in protein heterooligomerization IDA
IDA: Inferred from direct assay
31856708 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
25560148 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF777 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF777 Q9ULD5 KRTAP10-9 Homo sapiens P60411
Y2H Prey Pooling
32296183
Intra
ZNF777 Q9ULD5 KRTAP10-9 Homo sapiens P60411
Y2H Array
32296183
Intra
ZNF777 Q9ULD5 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
32296183
Intra
ZNF777 Q9ULD5 FAM9B Homo sapiens Q8IZU0
Y2H Array
32296183
Intra
ZNF777 Q9ULD5 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
ZNF777 Q9ULD5 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
ZNF777 Q9ULD5 IL16 Homo sapiens Q14005-2
Y2H Prey Pooling
32296183
Intra
ZNF777 Q9ULD5 IL16 Homo sapiens Q14005-2
Y2H Array
32296183
Intra
ZNF777 Q9ULD5 KIAA0753 Homo sapiens Q2KHM9
Y2H Prey Pooling
32296183
Intra
ZNF777 Q9ULD5 KIAA0753 Homo sapiens Q2KHM9
Y2H Array
32296183
Intra
ZNF777 Q9ULD5 FSD2 Homo sapiens A1L4K1
Y2H Array
32296183
Intra
ZNF777 Q9ULD5 FSD2 Homo sapiens A1L4K1
Y2H Prey Pooling
32296183
Intra
ZNF777 Q9ULD5 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
ZNF777 Q9ULD5 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
ZNF777 Q9ULD5 CLK3 Homo sapiens P49761
Y2H Prey Pooling
32296183
Intra
ZNF777 Q9ULD5 CLK3 Homo sapiens P49761
Validated Y2H
32296183
Intra
ZNF777 Q9ULD5 CLK3 Homo sapiens P49761
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16117 ZNF277 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16170 ZNF717 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16175 ZNF77 Human Pre-designed siRNA Set A Pre-designed Set / Unkown