2. Gene
  3. HTATSF1 - HIV-1 Tat specific factor 1 Gene

HTATSF1 - HIV-1 Tat specific factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as TATSF1; TAT-SF1; dJ196E23.2

Gene ID: 27336 | Gene type: protein coding

About HTATSF1

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:136,497,229-136,512,346 (from NCBI)

This gene has 4 transcripts (splice variants) and 217 orthologues. Ubiquitous expression in adrenal (RPKM 48.7), brain (RPKM 28.0) and 25 other tissues.

Summary

The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009]

HTATSF1 Products(2)

mRNA Protein Name
NM_001163280.2 NP_001156752.1 HIV Tat-specific factor 1
NM_014500.5 NP_055315.2 HIV Tat-specific factor 1

HTATSF1 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (135 - 212)

RRM_5

RRM_5: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (291 - 344)

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  • 755 a.a.
Protein Preferred Names Protein Names

HIV Tat-specific factor 1

HIV TAT specific factor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06454 HTATSF1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus HTATSF1 MGD MGI:1919709
Bos taurus HTATSF1 VGNC VGNC:29990
Macaca mulatta HTATSF1 VGNC VGNC:73535
Felis catus HTATSF1 VGNC VGNC:67666
Canis familiaris HTATSF1 VGNC VGNC:41822
Rattus norvegicus HTATSF1 RGD RGD:1563377