NPBWR2 - neuropeptides B and W receptor 2 Gene

Also Known as GPR8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2832

Summary

The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain. [provided by RefSeq, Jul 2008]

NPBWR2 Products (1)

mRNA Protein Name
NM_005286.4 NP_005277.2 neuropeptides B/W receptor type 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12401809 GOA
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12401809 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NPBWR2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NPBWR2 P48146 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra
NPBWR2 P48146 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
Intra
NPBWR2 P48146 KRTAP10-7 Homo sapiens P60409
Validated Y2H
25416956
Intra
NPBWR2 P48146 KRTAP10-7 Homo sapiens P60409
Y2H Array
25416956
Intra
NPBWR2 P48146 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
NPBWR2 P48146 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
NPBWR2 P48146 KPRP Homo sapiens Q5T749
Y2H Prey Pooling
32296183
Intra
NPBWR2 P48146 KPRP Homo sapiens Q5T749
Validated Y2H
32296183
Intra
NPBWR2 P48146 KPRP Homo sapiens Q5T749
Y2H Array
32296183
Intra
NPBWR2 P48146 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Array
32296183
Intra
NPBWR2 P48146 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Prey Pooling
32296183
Intra
NPBWR2 P48146 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra
NPBWR2 P48146 KRTAP6-2 Homo sapiens Q3LI66
Validated Y2H
32296183
Intra
NPBWR2 P48146 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Intra
NPBWR2 P48146 PNMA1 Homo sapiens Q8ND90
Validated Y2H
25416956
Intra
NPBWR2 P48146 PNMA1 Homo sapiens Q8ND90
Y2H Array
25416956
Intra
NPBWR2 P48146 PNMA1 Homo sapiens Q8ND90
Y2H Prey Pooling
25416956
Intra
NPBWR2 P48146 PSMA3 Homo sapiens P25788
Validated Y2H
25416956
Intra
NPBWR2 P48146 PSMA3 Homo sapiens P25788
Y2H Prey Pooling
25416956
Intra
NPBWR2 P48146 PSMA3 Homo sapiens P25788
Y2H Array
25416956
Intra
NPBWR2 P48146 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
NPBWR2 P48146 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
NPBWR2 P48146 NOTCH2NLA Homo sapiens Q7Z3S9
Validated Y2H
25416956
Intra
NPBWR2 P48146 NOTCH2NLA Homo sapiens Q7Z3S9
Y2H Prey Pooling
25416956
Intra
NPBWR2 P48146 NOTCH2NLA Homo sapiens Q7Z3S9
Y2H Array
25416956
Intra
NPBWR2 P48146 PHAF1 Homo sapiens Q9BSU1
Y2H Prey Pooling
32296183
Intra
NPBWR2 P48146 PHAF1 Homo sapiens Q9BSU1
Y2H Array
32296183
Intra
NPBWR2 P48146 PHAF1 Homo sapiens Q9BSU1
Validated Y2H
32296183
Intra
NPBWR2 P48146 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Intra
NPBWR2 P48146 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
NPBWR2 P48146 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
Intra
NPBWR2 P48146 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
NPBWR2 P48146 BOLL Homo sapiens Q8N9W6
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16382 NPBWR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20572 Npbwr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27080 Npbwr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown