GTF2E1 - general transcription factor IIE subunit 1 Gene
Also Known as FE; TF2E1; TFIIE-A
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 2960
Summary
Enables RNA polymerase II general transcription initiation factor activity. Involved in RNA polymerase II preinitiation complex assembly. Located in nucleoplasm. Part of transcription factor TFIID complex. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in testis (RPKM 6.1), lymph node (RPKM 3.7) and 25 other tissues.
GTF2E1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_005513.3 | NP_005504.2 | general transcription factor IIE subunit 1 |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables RNA polymerase II general transcription initiation factor activity |
IDA
IDA: Inferred from direct assay
|
27193682 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
7667268 | GOA |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| involved in transcription by RNA polymerase II |
IDA
IDA: Inferred from direct assay
|
27193682 | GOA |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
9841876 | GOA |
| part of transcription factor TFIID complex |
IDA
IDA: Inferred from direct assay
|
27193682 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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GTF2E1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
GTF2E1 | P29083 | TBC1D21 | Homo sapiens | Q8IYX1 | 32296183 | |
|
Intra
|
GTF2E1 | P29083 | GTF2E2 | Homo sapiens | P29084 | 32296183 | |
|
Intra
|
GTF2E1 | P29083 | NRARP | Homo sapiens | Q7Z6K4 | 32296183 | |
|
Intra
|
GTF2E1 | P29083 | GTF2H1 | Homo sapiens | P32780 | 18354501 | |
|
Intra
|
GTF2E1 | P29083 | GTF2H1 | Homo sapiens | P32780 | 32296183 | |
|
Intra
|
GTF2E1 | P29083 | GTF2H1 | Homo sapiens | P32780 | 18160537 | |
|
Intra
|
GTF2E1 | P29083 | GTF2H1 | Homo sapiens | P32780 | 18354501 |
Cross: Cross-species interaction
Intra: Intraspecies interaction