2. Gene
  3. TRA2A - transformer 2 alpha homolog Gene

TRA2A - transformer 2 alpha homolog Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as AWMS1; HSU53209

Gene ID: 29896 | Gene type: protein coding

About TRA2A

Cytogenetic location: 7p15.3 Genomic coordinates (GRCh38): 7:23,504,780-23,531,981 (from NCBI)

This gene has 12 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 46.2), endometrium (RPKM 25.7) and 25 other tissues.

Summary

This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

TRA2A Products(7)

mRNA Protein Name
NM_001282757.2 NP_001269686.1 transformer-2 protein homolog alpha isoform 2
NM_001282758.2 NP_001269687.1 transformer-2 protein homolog alpha isoform 2
NM_001282759.2 NP_001269688.1 transformer-2 protein homolog alpha isoform 3
NM_001362759.2 NP_001349688.1 transformer-2 protein homolog alpha isoform 4
NM_001362760.2 NP_001349689.1 transformer-2 protein homolog alpha isoform 2
NM_001362761.2 NP_001349690.1 transformer-2 protein homolog alpha isoform 2
NM_013293.5 NP_037425.1 transformer-2 protein homolog alpha isoform 1

TRA2A Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (123 - 191)

  • 0
  • 100
  • 200
  • 282 a.a.
Protein Preferred Names Protein Names

transformer-2 protein homolog alpha

TRA-2 alpha

Related Diseases

Diseases Alias
Malignant Pineal Area Germ Cell Neoplasm

Pineal Germ Cell Tumor

Malignant Pineal Parenchymal Germ Cell Tumor

Pineal Region Germ Cell Tumor

Pineal Cell Tumor

Pineal Cell Tumour

Pineal Region Germinoma

Malignant Pineal Region Germ Cell Tumor

Pineal Germinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14961 TRA2A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TRA2A VGNC VGNC:36267
Mus musculus TRA2A MGD MGI:1933972
Canis familiaris TRA2A VGNC VGNC:47758
Macaca mulatta TRA2A VGNC VGNC:79040
Rattus norvegicus TRA2A RGD RGD:1562563
Felis catus TRA2A VGNC VGNC:66490