Sp2 - Sp2 transcription factor Gene

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone deacetylase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including embryonic organ development; fibroblast proliferation; and in utero embryonic development. Predicted to be located in nucleoplasm. Orthologous to human SP2 (Sp2 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]