HSPD1 - heat shock protein family D (Hsp60) member 1 Gene

Also Known as HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 3329

About HSPD1

Cytogenetic location: 2q33.1 Genomic coordinates (GRCh38): 2:197,486,584-197,500,274 (from NCBI)

This gene has 24 transcripts (splice variants), 235 orthologues, 13 paralogues and is associated with 5 phenotypes. Ubiquitous expression in adrenal (RPKM 359.2), kidney (RPKM 152.5) and 24 other tissues.

Summary

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]

HSPD1 Products (2)

mRNA	Protein	Name
NM_002156.5	NP_002147.2	60 kDa heat shock protein, mitochondrial
NM_199440.2	NP_955472.1	60 kDa heat shock protein, mitochondrial

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables apolipoprotein A-I binding	IPI IPI: Inferred from physical interaction	11027668	GOA
enables apolipoprotein binding	IPI IPI: Inferred from physical interaction	11027668	GOA
enables double-stranded RNA binding	IDA IDA: Inferred from direct assay	21266579	GOA
enables enzyme binding	IPI IPI: Inferred from physical interaction	20507888	GOA
enables high-density lipoprotein particle binding	IDA IDA: Inferred from direct assay	11027668	GOA
enables lipopolysaccharide binding	IDA IDA: Inferred from direct assay	17164250	GOA
enables p53 binding	IPI IPI: Inferred from physical interaction	18086682	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	15846844	GOA
enables protein-folding chaperone binding	IPI IPI: Inferred from physical interaction	10205158	GOA
enables ubiquitin protein ligase binding	IPI IPI: Inferred from physical interaction	19725078	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in B cell activation	IDA IDA: Inferred from direct assay	16148103	GOA
involved in B cell proliferation	IDA IDA: Inferred from direct assay	16148103	GOA
involved in MyD88-dependent toll-like receptor signaling pathway	IDA IDA: Inferred from direct assay	16148103	GOA
acts upstream of or within T cell activation	IDA IDA: Inferred from direct assay	15371451	GOA
involved in activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA IDA: Inferred from direct assay	17823127	GOA
NOT involved in adhesion of symbiont to host	IDA IDA: Inferred from direct assay	20633027	GOA
involved in biological process involved in interaction with symbiont	IMP IMP: Inferred from mutant phenotype	20507888	GOA
involved in isotype switching to IgG isotypes	IDA IDA: Inferred from direct assay	16148103	GOA
involved in negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	17823127	GOA
involved in positive regulation of T cell activation	IDA IDA: Inferred from direct assay	16148103	GOA
involved in positive regulation of T cell mediated immune response to tumor cell	IDA IDA: Inferred from direct assay	10663613	GOA
involved in positive regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	17823127	GOA
involved in positive regulation of interferon-alpha production	IDA IDA: Inferred from direct assay	17164250	GOA
involved in positive regulation of interleukin-10 production	IDA IDA: Inferred from direct assay	16148103	GOA
involved in positive regulation of interleukin-12 production	IDA IDA: Inferred from direct assay	17164250	GOA
involved in positive regulation of interleukin-6 production	IDA IDA: Inferred from direct assay	16148103	GOA
involved in positive regulation of macrophage activation	IDA IDA: Inferred from direct assay	17164250	GOA
acts upstream of or within positive regulation of type II interferon production	IDA IDA: Inferred from direct assay	17164250	GOA
involved in positive regulation of type II interferon production	IDA IDA: Inferred from direct assay	17164250	GOA
involved in protein refolding	IDA IDA: Inferred from direct assay	11050098	GOA
involved in protein stabilization	IMP IMP: Inferred from mutant phenotype	18086682	GOA
involved in response to unfolded protein	IDA IDA: Inferred from direct assay	11050098	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in cell surface	IDA IDA: Inferred from direct assay	9243807	GOA
located in clathrin-coated pit	IDA IDA: Inferred from direct assay	11807771	GOA
located in coated vesicle	IDA IDA: Inferred from direct assay	11807771	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	21328542	GOA
located in cytosol	IDA IDA: Inferred from direct assay	17823127	GOA
located in early endosome	IDA IDA: Inferred from direct assay	11807771	GOA
located in extracellular exosome	IDA IDA: Inferred from direct assay	21276792	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	18229457	GOA
part of lipopolysaccharide receptor complex	IDA IDA: Inferred from direct assay	17164250	GOA
is active in mitochondrial matrix	IDA IDA: Inferred from direct assay	7865888	GOA
located in mitochondrial matrix	IDA IDA: Inferred from direct assay	19393246	GOA
located in mitochondrion	IDA IDA: Inferred from direct assay	17823127	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	11027668	GOA
part of protein-containing complex	IDA IDA: Inferred from direct assay	21328542	GOA
located in sperm midpiece	IMP IMP: Inferred from mutant phenotype	32791035	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HSPD1 Protein Structure

Cpn60_TCP1

0
100
200
300
400
500
573 a.a.

Protein Preferred Names	Protein Names
60 kDa heat shock protein, mitochondrial	60 kDa chaperonin

HSPD1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	HSPD1	P10809	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	25416956
Intra	HSPD1	P10809	RGS20	Homo sapiens	O76081-6	Y2H Prey Pooling	25416956
Intra	HSPD1	P10809	RGS20	Homo sapiens	O76081-6	Y2H Array	25416956
Intra	HSPD1	P10809	ESRP1	Homo sapiens	Q6NXG1	Validated Y2H	32814053
Intra	HSPD1	P10809	ESRP1	Homo sapiens	Q6NXG1	Y2H Array	32814053
Intra	HSPD1	P10809	ESRP1	Homo sapiens	Q6NXG1	Y2H Pooling	32814053
Intra	HSPD1	P10809	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	HSPD1	P10809	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	HSPD1	P10809	RGS20	Homo sapiens	O76081	Y2H Prey Pooling	25416956
Intra	HSPD1	P10809	IDH3G	Homo sapiens	P51553	Anti Tag CoIP	33961781
Intra	HSPD1	P10809	LIAT1	Homo sapiens	Q6ZQX7-4	Y2H Pooling	32814053
Intra	HSPD1	P10809	LIAT1	Homo sapiens	Q6ZQX7-4	Validated Y2H	32814053
Intra	HSPD1	P10809	LIAT1	Homo sapiens	Q6ZQX7-4	Y2H Array	32814053
Intra	HSPD1	P10809	CHAT	Homo sapiens	P28329-3	Y2H Pooling	32814053
Intra	HSPD1	P10809	CHAT	Homo sapiens	P28329-3	Validated Y2H	32814053
Intra	HSPD1	P10809	CHAT	Homo sapiens	P28329-3	Y2H Array	32814053
Intra	HSPD1	P10809	NEFH	Homo sapiens	P12036	Y2H Array	32814053
Intra	HSPD1	P10809	NEFH	Homo sapiens	P12036	Validated Y2H	32814053
Intra	HSPD1	P10809	NEFH	Homo sapiens	P12036	Y2H Pooling	32814053
Intra	HSPD1	P10809	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	HSPD1	P10809	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	HSPD1	P10809	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	HSPD1	P10809	CFTR	Homo sapiens	P13569	Ub Reconstruction	35156780
Intra	HSPD1	P10809	BRCA1	Homo sapiens	P38398	Pull Down	21988832
Intra	HSPD1	P10809	HRAS	Homo sapiens	P01112	Y2H Array	32814053
Intra	HSPD1	P10809	HRAS	Homo sapiens	P01112	Validated Y2H	32814053
Intra	HSPD1	P10809	HRAS	Homo sapiens	P01112	Y2H Pooling	32814053
Intra	HSPD1	P10809	ATAD3A	Homo sapiens	Q9NVI7	Anti Tag CoIP	22664726
Intra	HSPD1	P10809	ATAD3A	Homo sapiens	Q9NVI7	Anti Bait CoIP	22664726
Intra	HSPD1	P10809	DXO	Homo sapiens	O77932	Y2H Array	32814053
Intra	HSPD1	P10809	DXO	Homo sapiens	O77932	Y2H Pooling	32814053
Intra	HSPD1	P10809	DXO	Homo sapiens	O77932	Validated Y2H	32814053
Intra	HSPD1	P10809	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	HSPD1	P10809	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	HSPD1	P10809	DARS2	Homo sapiens	Q6PI48	Anti Tag CoIP	33961781
Intra	HSPD1	P10809	DARS2	Homo sapiens	Q6PI48	BioID	29568061
Intra	HSPD1	P10809	DARS2	Homo sapiens	Q6PI48	Anti Tag CoIP	28514442
Intra	HSPD1	P10809	BCAT2	Homo sapiens	O15382	Anti Tag CoIP	33961781
Intra	HSPD1	P10809	BCAT2	Homo sapiens	O15382	BioID	29568061
Intra	HSPD1	P10809	TP53BP1	Homo sapiens	Q12888	Validated Y2H	32814053
Intra	HSPD1	P10809	TP53BP1	Homo sapiens	Q12888	Y2H Pooling	32814053
Intra	HSPD1	P10809	TP53BP1	Homo sapiens	Q12888	Y2H Array	32814053
Intra	HSPD1	P10809	INCA1	Homo sapiens	Q0VD86	Validated Y2H	32814053
Intra	HSPD1	P10809	INCA1	Homo sapiens	Q0VD86	Y2H Pooling	32814053
Intra	HSPD1	P10809	INCA1	Homo sapiens	Q0VD86	Y2H Array	32814053
Intra	HSPD1	P10809	BOK	Homo sapiens	Q9UMX3	Y2H Pooling	32814053
Intra	HSPD1	P10809	BOK	Homo sapiens	Q9UMX3	Validated Y2H	32814053
Intra	HSPD1	P10809	BOK	Homo sapiens	Q9UMX3	Y2H Array	32814053
Intra	HSPD1	P10809	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	25416956
Intra	HSPD1	P10809	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	26871637
Intra	HSPD1	P10809	CEP70	Homo sapiens	Q8NHQ1	Validated Y2H	26871637
Intra	HSPD1	P10809	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	26871637
Intra	HSPD1	P10809	LZTS2	Homo sapiens	Q9BRK4	Validated Y2H	25910212
Intra	HSPD1	P10809	LZTS2	Homo sapiens	Q9BRK4	Y2H Prey Pooling	25416956
Intra	HSPD1	P10809	LZTS2	Homo sapiens	Q9BRK4	Y2H Array	25910212
Intra	HSPD1	P10809	LZTS2	Homo sapiens	Q9BRK4	Y2H Array	25416956
Intra	HSPD1	P10809	LZTS2	Homo sapiens	Q9BRK4	Y2H Bait-Prey Pool	25910212
Intra	HSPD1	P10809	SAMD3	Homo sapiens	Q8N6K7	Validated Y2H	25416956
Intra	HSPD1	P10809	SAMD3	Homo sapiens	Q8N6K7	Y2H Prey Pooling	25416956
Intra	HSPD1	P10809	SAMD3	Homo sapiens	Q8N6K7	Y2H Array	25416956
Intra	HSPD1	P10809	APP	Homo sapiens	P05067	Y2H Array	32814053
Intra	HSPD1	P10809	APP	Homo sapiens	P05067	Y2H Pooling	32814053
Intra	HSPD1	P10809	JUN	Homo sapiens	P05412	Y2H Pooling	32814053
Intra	HSPD1	P10809	JUN	Homo sapiens	P05412	Validated Y2H	32814053
Intra	HSPD1	P10809	JUN	Homo sapiens	P05412	Y2H Array	32814053
Intra	HSPD1	P10809	LASP1	Homo sapiens	Q14847-2	Validated Y2H	32814053
Intra	HSPD1	P10809	LASP1	Homo sapiens	Q14847-2	Y2H Array	32814053
Intra	HSPD1	P10809	LASP1	Homo sapiens	Q14847-2	Y2H Pooling	32814053
Intra	HSPD1	P10809	EYA3	Homo sapiens	Q99504	Validated Y2H	32814053
Intra	HSPD1	P10809	EYA3	Homo sapiens	Q99504	Y2H Array	32814053
Intra	HSPD1	P10809	EYA3	Homo sapiens	Q99504	Y2H Pooling	32814053
Intra	HSPD1	P10809	NOTCH2NLA	Homo sapiens	Q7Z3S9	Y2H Prey Pooling	25416956
Intra	HSPD1	P10809	KRT31	Homo sapiens	Q15323	Y2H Array	25416956
Cross	HSPD1	P10809	Smpd3	Mus musculus	Q9JJY3	Crosslink	23840630

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant HSPD1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73917	HSP60 Protein, Human (His-GST)	P10809-1 (L2-F573)	≥ 90%, as determined by reducing SDS-PAGE.

HSPD1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80184	Hsp60 Antibody (YA729)	WB, ICC/IF, IHC-P	Human, Mouse, Rat
HY-P80711	Hsp60 Antibody (YA730)	WB, ICC/IF, IP	Human, Mouse, Rat
HY-P80711A	Hsp60 Antibody (YA730)(PBS only)	WB, ICC/IF, IP	Human, Mouse, Rat
HY-P86546	Hsp60 Antibody (YA6238)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Spastic Paraplegia 13, Autosomal Dominant	SPG13 Hereditary Spastic Paraplegia 13 Autosomal Dominant Spastic Paraplegia 13 Spastic Paraplegia 13 Autosomal Dominant Spastic Paraplegia Type 13 Spastic Paraplegia-13 Paraplegia, Spastic, Type 13
Leukodystrophy, Hypomyelinating, 4	Mitochondrial Hsp60 Chaperonopathy Hypomyelinating Leukodystrophy 4 HLD4 Mitchap60 Disease Pelizaeus-Merzbacher-Like Disease Due To Hspd1 Mutation Mitchap-60 Disease Leukodystrophy, Hypomyelinating, Type 4
Reactive Arthritis	Postdysenteric Arthropathy Reiter Disease Pira Reiter Syndrome Reiters Syndrome Arthritis, Reactive Fiessinger Leroy Reiter Syndrome Post-Bacterial Arthropathy Reiter'S Disease Post-Infectious Arthritis Post-Infectious Reactive Arthropathy Reiter'S Syndrome Arthritis Urethritica Fiessinger-Leroy Disease Polyarthritis Enterica Venereal Arthritis Arthritis Reactive Post-Dysenteric Arthropathy Arthritis, Venereal
Chlamydia	Chlamydial Infection Chlamydia Trachomatis Infectious Disease Chlamydial Disease Chlamydia Infections
Vulvovaginitis	Vulvo-Vaginitis
Salpingitis
Paraplegia	Paraplegia, Lower Severe Or Complete Loss Of Motor Function In The Lower Extremities And Lower Portions Of The Trunk
Opportunistic Bacterial Infectious Disease
Nocardiosis	Nocardia Infection Nocardia Infections Nocardia Infectious Disease Lung Nocardiosis Nocardiasis Nocardiosis Nos
Bartonellosis	Bartonella Infections Bartonella Infectious Disease Bartonelliasis Rochalimaea Infection Bartonellosis, Unspecified
Carrion'S Disease	Oroya Fever Carrion Disease Bartonellosis Due To Bartonella Bacilliformis Infection Bartonella Infections Systemic Bartonellosis Due To Bartonella Bacilliformis Systemic Carrión Disease Systemic Bartonellosis Bartonella Fever
Epidemic Typhus	Typhus Typhus Fever Epidemic Louse-Borne Typhus Fever Due To Rickettsia Prowazekii Murine Typhus Classical Typhus Endemic Flea-Borne Typhus Endemic Typhus Fever Epidemic Louse-Borne Typhus Famine Fever Flea-Borne Typhus Jail Fever Louse-Borne Typhus Mexican Typhus Shop Typhus Urban Typhus Brill-Zinsser Disease Endemic Typhus Sylvatic Typhus Epidemic Typhus European Typhus Exanthematic Typhus Fever Exanthematous Typhus Flea Typhus Flea-Borne Rickettsiosis Hospital Fever Louse-Borne [Epidemic] Typhus Louse-Borne Rickettsiosis Moscow Typhus Murine [Endemic] Typhus Petechial Fever Prison Fever Rat Flea Typhus Ship Fever Typhus Exanthematique Typhus, Endemic Flea-Borne Typhus, Epidemic Louse-Borne Typhus Group Rickettsial Disease Relapsing Fever Typhus Fever Nos Typhus Nos Epidemic Typhus Fever Louse-Borne Typhus Fever Classical Typhus Fever Louse-Borne Tabardillo Epidemic Typhus Fever Due To Rickettsia Prowazekii Endemic Murine Typhus Flea-Borne Typhus Fever Murine Endemic Flea Typhus Rat Typhus Typhus Due To Rickettsia Typhi Flea-Borne Tabardillo Rickettsia Typhi Rickettsiosis Mexican Fever Murine Flea-Borne Typhus Mooser Bodies Tsutsugamushi Fever Kedani Fever Mite-Borne Typhus Mite-Borne Typhus Due To Rickettsia Tsutsugamushi Scrub Typhus Tsutsugamushi Tsutsugamushi Disease Scrub Mite-Borne Typhus Sumatran Mite Fever Japanese River Fever Kedani Typhus Rickettsia Tsutsugamushi Rickettsiosis Sumatran Mite Typhus Tropical Typhus Japanese Typhus
Autoimmune Atherosclerosis
Sennetsu Fever	Sennetsu Ehrlichiosis Human Ehrlichial Infection, Sennetsu Type
Mycobacterium Fortuitum
Urethritis	Nonspecific Urethritis Non-Gonococcal Urethritis Nongonococcal Urethritis
Endocarditis
Glanders	Farcy Pipes Infection Due To Pseudomonas Mallei Burkholderia Mallei Burkholderia Mallei Infection Equina Equine Glanders Farcy Farcy Buds Farcy Cords Infection Due To Actinobacillus Mallei Infection Due To Malleomyces Mallei Maliasmus Malleus Farce Actinobacillosis Actinobacillus Infection
Type 1 Diabetes Mellitus	Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus Type 1 IDDM Type 1 Diabetes Insulin-Dependent Diabetes Mellitus T1D Juvenile-Onset Diabetes Jod Diabetes Mellitus, Type 1 Diabetes Mellitus, Insulin-Dependent-1 Type I Diabetes Mellitus Autoimmune Diabetes Juvenile Diabetes Juvenile-Onset Diabetes Mellitus Diabetes, Insulin Dependent Insulin-Dependent Diabetes Mellitus-1 Diabetes Mellitus Insulin-Dependent Diabetes Autoimmune Diabetes Mellitus, Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 1, Susceptibility To Diabetes Type 1 Type I Diabetes Diabetes, Autoimmune T1dm - [Type 1 Diabetes Mellitus] Iddm - [Insulin Dependent Diabetes Mellitus] Type 1 Iddm Juvenile Diabetes Mellitus Without Compications Idiopathic Insulin-Dependent Diabetes Mellitus Without Complications Juvenile-Onset Diabetes Mellitus Without Compications Ketosis-Prone Diabetes Mellitus Without Compications Juvenile-Onset-Type Diabetes Mellitus Without Compications
Mixed Connective Tissue Disease	Sharp Syndrome Mctd Connective Tissue Disease Overlap Syndrome Mixed Collagen Vascular Disease Mctd - [Mixed Connective Tissue Disease]
Lyme Disease	Lyme Borreliosis Lyme Neuroborreliosis Borreliosis Borrelia Burgdorferi Infection Neuroborreliosis Bannwarth Syndrome Bannworth'S Syndrome Neurological Lyme Disease B. Burgdorferi Infection Borreliosis, Lyme Infection By Borrelia Burgdorferi Infection Due To Borrelia Burgdorferi Sensu Lato Lym Borrelia Infections
Hypomyelinating Leukodystrophy	Hld Leukodystrophy, Hypomyelinating
Oral Lichen Planus	Oral Lichenoid Lesions Lichen Planus Oral Lichen Planus, Oral
Kawasaki Disease	Mucocutaneous Lymph Node Syndrome Acute Febrile Mucocutaneous Lymph Node Syndrome Kawasaki Syndrome Kd Infantile Polyarteritis Kawasaki Disease, Susceptibility To Acute Febrile Mcls Kawasaki'S Disease Mlns KWD
Mycobacterium Tuberculosis 1	Tuberculosis Tuberculoma Tuberculosis, Susceptibility To Mycobacterium Tuberculosis, Susceptibility To, 1 Mtbs1 TB
Endemic Typhus	Murine Typhus Cat Flea Rickettsiosis Fleaborne Typhus Rat-Flea Typhus Rickettsia Felis Spotted Fever Shop Typhus Toulon Typhus Urban Typhus Urban Typhus Of Malaya Flea-Borne Typhus Endemic Flea-Borne Typhus
Pelvic Inflammatory Disease	Pid
Cat-Scratch Disease	Cat Scratch Disease Benign Lymphoreticulosis Cat Scratch Fever Debre'S Syndrome Bartonellosis Due To Bartonella Henselae Infection Debre-Mollaret Syndrome Foshay-Mollaret Cat Scratch Fever Oroya Fever Cat-Scratch Fever Benign Inoculation Lymphoreticulosis Catscratch Disease Or Fever Csd - [Cat Scratch Disease] Nonbacterial Regional Lymphadenitis Rochalimaea Henselae Infection
Trench Fever	His-Werner Disease Quintan Fever Shin Bone Fever Wolhynian Fever Tibialgic Fever Bartonellosis Due To Bartonella Quintana Infection Febris Quintata Five Day Fever Fever Due To Rickettsia Quintana Febris Quintana Fever Due To Bartonella Quintana Fever Due To Rochalimaea Quintana Meuse Fever
Tick Infestation	Tick Infestations
Arteriosclerosis	Arteriosclerotic Vascular Disease
Lepromatous Leprosy	Leprosy, Lepromatous Type L Leprosy Leprosy Lepromatous
Leukodystrophy	Leukodystrophies
Haverhill Fever	Streptobacillosis Streptobacillary Rat-Bite Fever Streptobacillary Fever Rat-Bite Fever Due To Streptobacillus Moniliformis Erythema Arthriticum Epidemicum Epidemic Arthritic Erythema
Whipple Disease	Intestinal Lipodystrophy Whipple'S Disease Intestinal Lipophagic Granulomatosis Secondary Non-Tropical Sprue Tropheryma Whippelii Infection Whipples Disease
Bacillary Angiomatosis	Angiomatosis, Bacillary
Human Granulocytic Anaplasmosis	Human Granulocytic Ehrlichiosis Hge Human Ehrlichial Infection, Human Granulocytic Type Human Anaplasmosis Due To Anaplasma Phagocytophilum
Uveitis
Mitochondrial Myopathy	Mitochondrial Myopathies Mitochondrial Cytopathy Myopathies In Mitochondrial Disorders
Autoimmune Disease	Autoimmune Diseases Autoimmune Hypersensitivity Disease Hypersensitivity Reaction Type Ii Disease Type Ii Hypersensitivity Reaction Disease
Mitochondrial Encephalomyopathy	Mitochondrial Encephalomyopathies Encephalomyopathy, Mitochondrial
Hereditary Spastic Paraplegia	Familial Spastic Paraplegia Hereditary Spastic Paraparesis Strumpell-Lorrain Disease Familial Spastic Paraparesis Hsp Spg Strümpell-Lorrain Disease Spastic Paraplegia, Hereditary French Settlement Disease Strumpell-Lorrain Syndrome Fsp Spastic Paraplegia, Familial Spastic Paraplegia Hereditary Spastic Paraplegia 3, Autosomal Dominant Spastic Paraparesis Hereditary Spastic Paralysis Familial Spastic Paralysis Hereditary Spastic Ataxia
Tick-Borne Relapsing Fever	Relapsing Fever, Tick-Borne Relapsing Fever Due To Any Borrelia Species Other Than Borrelia Recurrentis African Tick-Borne Fever
Cervicitis	Uterine Cervicitis Inflammation Of Cervix
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Sudden Infant Death Syndrome	SIDS Sudden Infant Death Syndrome, Susceptibility To Cot Death Crib Death Sudden Death Of Nonspecific Cause In Infancy Sudden Infant Death Death, Sudden, Syndrome, Infant
Ectopic Pregnancy	Eccyesis Pregnancy Ectopic Pregnancy, Ectopic Ectopic Pregnancies Extrauterine Gestation Or Pregnancy Extrauterine Pregnancy Ep - [Ectopic Pregnancy] Ectopic Mole Aborted Ectopic Pregnancy Ruptured Ectopic Pregnancy
Ehrlichiosis	Human Ehrlichiosis He Hey
Vasculitis	Angiitis Autoimmune Vasculitis Systemic Vasculitis Vasculitis, Autoimmune
Autoimmune Hepatitis	Aih Hepatitis, Autoimmune Autoimmune Chronic Active Hepatitis Autoimmune Hepatitis With Centrilobular Necrosis Autoimmune Chronic Hepatitis Hepatitis Autoimmune
Chronic Endophthalmitis
Disease By Infectious Agent	Infectious Disease Infectious Diseases
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behçet'S Disease Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease
Juvenile Rheumatoid Arthritis	Juvenile Idiopathic Arthritis Juvenile Chronic Polyarthritis Monarticular Juvenile Rheumatoid Arthritis Pauciarticular Juvenile Arthritis Still'S Disease Systemic Juvenile Rheumatoid Arthritis Juvenile Chronic Arthritis Acute Juvenile Rheumatoid Arthritis Pauciarticular Onset Juvenile Chronic Arthritis Arthritis, Juvenile Rheumatoid Jia Jra Juvenile Ra Arthritis Juvenile Rheumatoid Stills Disease Juvenile Arthritis Acute Polyarticular Juvenile Rheumatoid Arthritis Pauciarticular Juvenile Rheumatoid Arthritis Rheumatoid Arthritis, Systemic Juvenile
Far Eastern Spotted Fever	Rickettsia Heilongjiangensis Spotted Fever
Inclusion Conjunctivitis	Chlamydial Conjunctivitis Inclusion Blennorrhoea Paratrachoma Adult Inclusion Conjunctivitis Inclusion Blenorrhea Conjunctivitis, Inclusion Neonatal Chlamydial Conjunctivitis Inclusion Conjunctivitis Of The Adult Chronic Conjunctivitis Due To Chlamydia Trachomatis Inclusion Conjunctivitis Due To Chlamydia Trachomatis Acute Follicular Conjunctivitis, Chlamydial Adult Chlamydial Keratoconjunctivitis
Heterophyiasis	Heterophyes Infectious Disease
Arthritis	Inflammatory Joint Disease Inflammatory Disorder Of Joint
Macs Syndrome	Macrocephaly, Alopecia, Cutis Laxa, And Scoliosis Mycobacterium Avium Complex Disease Rin2 Syndrome Mycobacterium Avium-Intracellulare Infection Tall Forehead, Sparse Hair, Skin Hyperextensibility, And Scoliosis Mycobacterium Avium Complex Mycobacterium Avium Infection Infection Due To Mycobacterium Intracellulare Mac Disease Macrocephaly-Alopecia-Cutis Laxa-Scoliosis Syndrome Rin2 Deficiency Tall Forehead-Sparse Hair-Skin Hyperextensibility-Scoliosis Syndrome MACS Macrocephaly Alopecia Cutis Laxa And Scoliosis Syndrome
Parasitic Ectoparasitic Infectious Disease	Ectoparasitic Infestations Ectoparasitism
Atherosclerosis Susceptibility	Atherosclerosis Atherosclerosis, Susceptibility To ATHS Atherogenic Lipoprotein Phenotype Alp Arteriosclerosis
Human Monocytic Ehrlichiosis	Ehrlichiosis Chafeensis Hme Human Ehrlichial Infection, Human Monocytic Type
Spondyloarthropathy 1	Ankylosing Spondylitis Spondyloarthropathy, Susceptibility To, 1 SPDA1 Marie-Strumpell Spondylitis Bechterew Syndrome Spa Spondylarthritis Ankylopoietica Reiter Syndrome Ankylosing Spondylitis, Susceptibility To Bekhterev Syndrome Bekhterev'S Disease Marie-Strumpell Disease Axial Spondylarthritis Bechterew Disease Marie-Struempell Disease Spondylitis Ankylopoietica Spondyloarthritis Spondyloarthritis Ankylopoietica Spas Ankylosing Spondylarthritis Psoriatic Arthritis Reactive Arthritis Rheumatoid Spondylitis Spondylitis Ankylosans Spondylitis Ankylosing Spondylitis, Ankylosing Spondylarthropathies Arthritis, Psoriatic Arthritis, Reactive
Tularemia	Francisella Tularensis Infection Deerfly Fever Lemming Fever Ohara Disease Pahvant Valley Plague Rabbit Fever Yatobyo
Chancroid	Ulcus Molle, Skin Chancroids Bubo Due To Haemophilus Ducreyi Soft Chancre Ulcus Molle
Relapsing Fever	Febris Recurrens Novy Febris Recurrens Novy Relapsing Fever
Endocardium Disease
Rocky Mountain Spotted Fever	Brazillian Spotted Choix Exanthematic Typhus Of Sao Paulo Fiebre Maculosa Fiebre Manchada Sao Paulo Typhus So Paulo Fever Tick Typhus Tobia Fever Rmsf Typhus, Tick
Multidrug-Resistant Tuberculosis	Tuberculosis, Multidrug-Resistant Tuberculosis Multidrug-Resistant
Lymphoma, Mucosa-Associated Lymphoid Type	Malt Lymphoma Gastric Lymphoma, Primary Lymphoma, Malt, Somatic Mucosa-Associated Lymphoid Tissue Lymphoma Extranodal Marginal Zone B-Cell Lymphoma MALTOMA Marginal Zone B-Cell Lymphoma Mucosa-Associated Lymphatic Tissue Lymphoma Primary Gastric Lymphoma Gastric Lymphoma Familial Primary Gastric Lymphoma
Bacterial Infectious Disease	Bacterial Infections Bacterial Infection Nos Disease Caused By Bacteria Bacterial Disease Or Disorder
Metagonimiasis	Trematode Infections Infection By Metagonimus Yokogawai Metagonimus Yokogawai Infection
Spotted Fever	Spotted Fevers Spotted Fever Group Rickettsial Disease Tick-Borne Rickettsioses Tick-Borne Typhus Nos Rocky Mountain Spotted Fever Sao Paulo Fever Sao Paulo Typhus Lone Star Spotted Fever Colombian Spotted Fever American Spotted Fever Tick Typhus Due To Rickettsia Rickettsii Rocky Mountain Tick Fever Boutonneuse Fever Mediterranean Tick Fever Fièvre Boutonneuse Mediterranean Spotted Fever Tick Typhus Due To Rickettsia Conorii African Tick Typhus Indian Tick Typhus Kenya Tick Typhus North Asian Tick Fever Siberian Tick Typhus Tick Typhus Due To Rickettsia Siberica North Asian Spotted Fever Queensland Tick Typhus Queensland Fever
Olecranon Bursitis	Bursitis Of Elbow Bursitis Of Elbow Region Capped Elbow Elbow Bursitis Miner'S Elbow Miners' Elbow Shoe Boil
Vascular Disease	Vascular Diseases Aneurysm Spinal Cord Ischemia Vascular Anomaly Spinal Cord Vascular Diseases Vascular Tissue Disease
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Primary Bacterial Infectious Disease
Actinomycosis	Actinomycetoma Boil Canaliculitis Actinomycotic Infection Actinomycotic Madura Foot Keratoactinomycosis Furuncle Actinomycotic Mycetema Actinomycotic Mycetoma Of Foot Madura Foot Due To Actinomadura Actinomyces Israeli Actinomycetes Anaerobic Actinomyces Infection Actinomycotic Infection Of Unspecified Site Actinomycosis Nos Actinomycotic Node Actinomyces Infection Actinomycotic Mycetoma Mycetoma Due To Filamentous Bacteria
Megalencephalic Leukoencephalopathy With Subcortical Cysts 2a	MLC2A Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, 2a Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, Type 2a
Mitochondrial Complex Iv Deficiency, Nuclear Type 5	Leigh Syndrome, French Canadian Type Mitochondrial Complex V Deficiency Nuclear Type 4 Cytochrome C Oxidase Deficiency, French Canadian Type Lsfc Cox Deficiency, French Canadian Type MC5DN4 MC4DN5 Cox Deficiency, Saguenay-Lac-Saint-Jean Type Leigh Syndrome, Saguenay-Lac-Saint-Jean Type Mitochondrial Complex V Deficiency, Nuclear Type 4 French Canadian Leigh Disease Leigh Syndrome, French-Canadian Type Leigh Syndrome , French Canadian Type Mitochondrial Complex V Deficiency, Atp5a1 Type French Canadian Type Cox Deficiency French Canadian Type Cytochrome C Oxidase Deficiency French Canadian Type Leigh Syndrome Saguenay Lac Saint Jean Type Cox Deficiency Saguenay Lac Saint Jean Type Leigh Syndrome Cox Deficiency, Saguenay Lac Saint Jean Type Leigh Syndrome, Saguenay Lac Saint Jean Type Mitochondrial Complex V Deficiency, Nuclear Type 4 Mitochondrial Complex V Deficiency Atp5a1 Type Mitochondrial Complex V Deficiency Type 4 Mitochondrial Complex V Deficiency, Nuclear, Type 4
Campylobacteriosis	Campylobacter Infections Campylobacter Infection Enteric Campylobacteriosis
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Cervical Adenitis	Cervical Lymphadenitis
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Endocervicitis
Tenosynovitis	Inflammation Of Tendon Sheath Synovitis Or Tenosynovitis
Babesiosis	Babesiasis Infection By Babesia Piroplasmosis Human Babesiosis Babesia Parasite Infection Piroplasma Infection
Ornithosis	Psittacosis Chlamydial Pneumonia Chlamydia Psittaci Infection Chlamydia Psittaci
Deep Keratitis
Primary Systemic Mycosis
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Amyotrophic Lateral Sclerosis 3	ALS3 Amyotrophic Lateral Sclerosis Type 3
Boutonneuse Fever	Mediterranean Spotted Fever African Tick Typhus Boutonneuse Disease Conor And Bruch'S Disease Kenya Fever Kenya Tick Typhus Kenyan Tick Typhus Marseilles Fever Mediterranean Tick Fever Rickettsia Conorii Spotted Fever South African Tick-Bite Fever African Tick Bite Fever
Leprosy 3	Leprosy Leprosy, Susceptibility To, 3 Hansen'S Disease Leprosy, Susceptibility To Hansen Disease Infection Due To Mycobacterium Leprae LPRS3 Leprosy, Type 3 Anaesthesia Leprosy Anaesthetic Leprosy Maculoanaesthetic Leprosy Macular Leprosy Leprosy Unspecified
Acute Disseminated Encephalomyelitis	Acute Disseminated Encephalitis Adem Ade Encephalomyelitis Acute Disseminated Encephalomyelitis, Acute Disseminated Adem - [Acute Disseminated Encephalomyelitis]
Commensal Bacterial Infectious Disease
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Theileriasis	Theileriosis Infection By Theileria
Vaginitis	Infective Vaginitis Inflammation Of Vagina Colpitis Vaginal Inflammation Vaginitis Nos
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Septic Arthritis	Infectious Arthritis Arthritis, Infectious Arthritis Septic Arthritis, Bacterial
Lymph Node Disease	Abnormality Of The Lymph Nodes Disorder Of Lymph Node
Complement Component 7 Deficiency	C7 Deficiency C7D
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Primary Biliary Cholangitis	Primary Biliary Cirrhosis Biliary Liver Cirrhosis Chronic Nonsuppurative Destructive Cholangitis Familial Primary Biliary Cirrhosis Pbc Hanot Syndrome Cholestatic Cirrhosis Biliary Cirrhosis Primary Liver Cirrhosis, Biliary Hanot'S Cirrhosis Biliary Cirrhosis Pericholangiolic Biliary Cirrhosis Tannhauser-Magendantz Syndrome Hanot-Rossle Syndrome Hypertrophic Cirrhosis Todd Cirrhosis Hanot Cirrhosis Charcot Cirrhosis Mahon-Tannhauser Syndrome Toxic Cirrhosis Hypertrophic Biliary Cirrhosis Monolobular Cirrhosis Unilobar Cirrhosis Xanthomatous Biliary Cirrhosis
Cardiovascular System Disease	Abnormality Of The Cardiovascular System Cardiovascular Disease Disease Of Subdivision Of Hemolymphoid System Disorder Of Cardiovascular System Cardiovascular Diseases
Diabetes Mellitus	Diabetes
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Parkinson Disease, Late-Onset	Parkinson Disease Parkinson'S Disease PD PARK Parkinson Disease, Susceptibility To Late Onset Parkinson'S Disease Late Onset Parkinson Disease Paralysis Agitans Primary Parkinsonism Idiopathic Parkinson Disease Parkinson'S Parkinson Disease, Late-Onset, Susceptibility To Parkinson Disease, Age Of Onset, Modifier Lewy Body Parkinson Disease Idiopathic Parkinson'S Disease Pd - [Parkinson Disease] Parkinson Disease Nos Parkinson, Nos Primary Parkinson Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0890	Tubeimoside I		99.96%	Unkown
HY-115715	EN219		99.21%	Unkown
HY-10996A	KHS101 hydrochloride		99.65%	Unkown
HY-115715A	EN219-alkyne		99.62%	Unkown
HY-10996	KHS101		/	Unkown
HY-N0890R	Tubeimoside I (Standard)	Inducer	/	Unkown
HY-RS06447	HSPD1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS18520	Hspd1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS25002	Hspd1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	HSPD1	VGNC	VGNC:82530
Rattus norvegicus	HSPD1	RGD	RGD:621314
Mus musculus	HSPD1	MGD	MGI:96242
Bos taurus	HSPD1	VGNC	VGNC:49070
Others	HSPD1	NCBI