BEX5 - brain expressed X-linked 5 Gene

Also Known as NGFRAP1L1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 340542

About BEX5

Cytogenetic location: Xq22.1 Genomic coordinates (GRCh38): X:102,153,712-102,155,977 (from NCBI)

This gene has 3 transcripts (splice variants), 60 orthologues and 3 paralogues. Biased expression in brain (RPKM 24.8), thyroid (RPKM 6.2) and 10 other tissues.

Summary

Predicted to enable signaling receptor binding activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

BEX5 Products (2)

mRNA Protein Name
NM_001012978.3 NP_001012996.1 protein BEX5
NM_001159560.2 NP_001153032.1 protein BEX5

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BEX5 Protein Structure

BEX

BEX: Brain expressed X-linked like family (1 - 110)

  • 0
  • 100
  • 111 a.a.
Protein Preferred Names Protein Names

protein BEX5

  • BEX family member 5

BEX5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
BEX5 Q5H9J7 GOLGA8F Homo sapiens Q08AF8
Y2H Prey Pooling
25416956
Intra
BEX5 Q5H9J7 MAGEA8 Homo sapiens P43361
Validated Y2H
25416956
Intra
BEX5 Q5H9J7 MAGEA8 Homo sapiens P43361
Y2H Array
29892012
Intra
BEX5 Q5H9J7 MAGEA8 Homo sapiens P43361
Y2H Array
31515488
Intra
BEX5 Q5H9J7 MAGEA8 Homo sapiens P43361
Y2H Prey Pooling
25416956
Intra
BEX5 Q5H9J7 FKBP1A Homo sapiens Q0VDC6
Validated Y2H
32814053
Intra
BEX5 Q5H9J7 FKBP1A Homo sapiens Q0VDC6
Y2H Array
32814053
Intra
BEX5 Q5H9J7 FKBP1A Homo sapiens Q0VDC6
Y2H Pooling
32814053
Intra
BEX5 Q5H9J7 MORF4L1 Homo sapiens Q9UBU8-2
Validated Y2H
32296183
Intra
BEX5 Q5H9J7 GTF3C3 Homo sapiens Q9Y5Q9
Validated Y2H
32814053
Intra
BEX5 Q5H9J7 GTF3C3 Homo sapiens Q9Y5Q9
Y2H Array
32814053
Intra
BEX5 Q5H9J7 GTF3C3 Homo sapiens Q9Y5Q9
Y2H Pooling
32814053
Intra
BEX5 Q5H9J7 PACRGL Homo sapiens Q8N7B6-2
Validated Y2H
32296183
Intra
BEX5 Q5H9J7 DMWD Homo sapiens G5E9A7
Validated Y2H
32814053
Intra
BEX5 Q5H9J7 DMWD Homo sapiens G5E9A7
Y2H Pooling
32814053
Intra
BEX5 Q5H9J7 DMWD Homo sapiens G5E9A7
Y2H Array
32814053
Intra
BEX5 Q5H9J7 GNG13 Homo sapiens Q9P2W3
Validated Y2H
32296183
Intra
BEX5 Q5H9J7 FOXD4L3 Homo sapiens Q6VB84
Validated Y2H
32296183
Intra
BEX5 Q5H9J7 COPS7B Homo sapiens Q9H9Q2
Validated Y2H
32296183
Intra
BEX5 Q5H9J7 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra
BEX5 Q5H9J7 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra
BEX5 Q5H9J7 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra
BEX5 Q5H9J7 GSN Homo sapiens P06396
Validated Y2H
32814053
Intra
BEX5 Q5H9J7 GSN Homo sapiens P06396
Y2H Array
32814053
Intra
BEX5 Q5H9J7 GSN Homo sapiens P06396
Y2H Pooling
32814053
Intra
BEX5 Q5H9J7 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
BEX5 Q5H9J7 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
BEX5 Q5H9J7 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
BEX5 Q5H9J7 EMILIN1 Homo sapiens Q9Y6C2
Y2H Array
25416956
Intra
BEX5 Q5H9J7 EMILIN1 Homo sapiens Q9Y6C2
Y2H Prey Pooling
25416956
Intra
BEX5 Q5H9J7 EMILIN1 Homo sapiens Q9Y6C2
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Childhood Supratentorial Ependymoma

  • Paediatric Cerebral Ependymoma

  • Paediatric Supratentorial Ependymoblastoma

  • Paediatric Supratentorial Ependymoma

  • Pediatric Cerebral Ependymoma

  • Pediatric Supratentorial Ependymoblastoma

  • Pediatric Supratentorial Ependymoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01484 BEX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus BEX5 VGNC VGNC:50553
Rattus norvegicus BEX5 RGD RGD:6488322
Canis familiaris BEX5 VGNC VGNC:54663
Others BEX5 NCBI