COPS7B - COP9 signalosome subunit 7B Gene

Also Known as CSN7B; SGN7b

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64708

Summary

Involved in protein deneddylation. Located in nucleoplasm. Part of COP9 signalosome. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in testis (RPKM 9.9), lymph node (RPKM 6.4) and 25 other tissues.

COPS7B Products (7)

mRNA Protein Name
NM_001282949.3 NP_001269878.1 COP9 signalosome complex subunit 7b isoform c
NM_001282950.3 NP_001269879.1 COP9 signalosome complex subunit 7b isoform a
NM_001282951.3 NP_001269880.1 COP9 signalosome complex subunit 7b isoform d
NM_001282952.3 NP_001269881.1 COP9 signalosome complex subunit 7b isoform e
NM_001308381.2 NP_001295310.1 COP9 signalosome complex subunit 7b isoform f
NM_001369483.1 NP_001356412.1 COP9 signalosome complex subunit 7b isoform b
NM_022730.4 NP_073567.1 COP9 signalosome complex subunit 7b isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in protein deneddylation IDA
IDA: Inferred from direct assay
19141280 GOA
Cellular Component GO Annotation Evidence References Source
part of COP9 signalosome IDA
IDA: Inferred from direct assay
18850735 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

COPS7B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
COPS7B Q9H9Q2 BEX5 Homo sapiens Q5H9J7
Y2H Array
32296183
Intra
COPS7B Q9H9Q2 BEX5 Homo sapiens Q5H9J7
Y2H Prey Pooling
32296183
Intra
COPS7B Q9H9Q2 HSPB1 Homo sapiens P04792
Validated Y2H
32814053
Intra
COPS7B Q9H9Q2 HSPB1 Homo sapiens P04792
Y2H Array
32814053
Intra
COPS7B Q9H9Q2 HSPB1 Homo sapiens P04792
Y2H Pooling
32814053
Intra
COPS7B Q9H9Q2 CCT5 Homo sapiens P48643
Y2H Array
32814053
Intra
COPS7B Q9H9Q2 CCT5 Homo sapiens P48643
Y2H Pooling
32814053
Intra
COPS7B Q9H9Q2 CCT5 Homo sapiens P48643
Validated Y2H
32814053
Intra
COPS7B Q9H9Q2 NMI Homo sapiens Q13287
Y2H Prey Pooling
25416956
Intra
COPS7B Q9H9Q2 NMI Homo sapiens Q13287
Validated Y2H
25416956
Intra
COPS7B Q9H9Q2 NMI Homo sapiens Q13287
Y2H Prey Pooling
32296183
Intra
COPS7B Q9H9Q2 NMI Homo sapiens Q13287
Y2H Array
25416956
Intra
COPS7B Q9H9Q2 NMI Homo sapiens Q13287
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

COPS7B Antibodies

Cat. No. Product Name Application Reactivity
HY-P811361 COPS7B Antibody WB, IHC-P, FC Human