GTF3C3 - general transcription factor IIIC subunit 3 Gene

Also Known as NEDFBS; TFIIIC102; TFIIICgamma; TFiiiC2-102

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9330

Summary

The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Ubiquitous expression in testis (RPKM 7.9), thyroid (RPKM 6.7) and 25 other tissues.

GTF3C3 Products (1)

mRNA Protein Name
NG_030373.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase III general transcription initiation factor activity IDA
IDA: Inferred from direct assay
17409385 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
17314511 GOA
Cellular Component GO Annotation Evidence References Source
part of transcription factor TFIIIC complex IDA
IDA: Inferred from direct assay
17409385 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GTF3C3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GTF3C3 Q9Y5Q9 USP2 Homo sapiens O75604-3
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 USP2 Homo sapiens O75604-3
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 USP2 Homo sapiens O75604-3
Y2H Pooling
32814053
Intra
GTF3C3 Q9Y5Q9 GTF3C4 Homo sapiens Q9UKN8
Anti Tag CoIP
33961781
Intra
GTF3C3 Q9Y5Q9 DPP9 Homo sapiens Q86TI2-2
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 DPP9 Homo sapiens Q86TI2-2
Y2H Pooling
32814053
Intra
GTF3C3 Q9Y5Q9 DPP9 Homo sapiens Q86TI2-2
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 ANXA8 Homo sapiens P13928
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 ANXA8 Homo sapiens P13928
Y2H Pooling
32814053
Intra
GTF3C3 Q9Y5Q9 ANXA8 Homo sapiens P13928
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 HES4 Homo sapiens Q9HCC6
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 HES4 Homo sapiens Q9HCC6
Y2H Pooling
32814053
Intra
GTF3C3 Q9Y5Q9 HES4 Homo sapiens Q9HCC6
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 MYC Homo sapiens P01106
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 MYC Homo sapiens P01106
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 MYC Homo sapiens P01106
Y2H Pooling
32814053
Intra
GTF3C3 Q9Y5Q9 HTT Homo sapiens P42858
Y2H
17500595
Intra
GTF3C3 Q9Y5Q9 SAP30 Homo sapiens O75446
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 SAP30 Homo sapiens O75446
Y2H Pooling
32814053
Intra
GTF3C3 Q9Y5Q9 SAP30 Homo sapiens O75446
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 STRN4 Homo sapiens Q9NRL3
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 STRN4 Homo sapiens Q9NRL3
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 STRN4 Homo sapiens Q9NRL3
Y2H Pooling
32814053
Intra
GTF3C3 Q9Y5Q9 MPC2 Homo sapiens O95563
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 MPC2 Homo sapiens O95563
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 MPC2 Homo sapiens O95563
Y2H Pooling
32814053
Intra
GTF3C3 Q9Y5Q9 SPPL2B Homo sapiens Q8TCT7-2
Y2H Array
32814053
Intra
GTF3C3 Q9Y5Q9 SPPL2B Homo sapiens Q8TCT7-2
Validated Y2H
32814053
Intra
GTF3C3 Q9Y5Q9 SPPL2B Homo sapiens Q8TCT7-2
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS05906 GTF3C1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05907 GTF3C2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown