OTOP3 - otopetrin 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 347741

Summary

Predicted to enable identical protein binding activity and proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jun 2026]
Biased expression in duodenum (RPKM 38.1), small intestine (RPKM 6.4) and 1 other tissue.

OTOP3 Products (2)

mRNA Protein Name
NM_001272005.2 NP_001258934.1 proton channel OTOP3 isoform 2
NM_178233.2 NP_839947.1 proton channel OTOP3 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OTOP3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
OTOP3 Q7RTS5 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra
OTOP3 Q7RTS5 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra
OTOP3 Q7RTS5 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra
OTOP3 Q7RTS5 SLC13A4 Homo sapiens Q9UKG4
Y2H Prey Pooling
32296183
Intra
OTOP3 Q7RTS5 SLC13A4 Homo sapiens Q9UKG4
Validated Y2H
32296183
Intra
OTOP3 Q7RTS5 SLC13A4 Homo sapiens Q9UKG4
Y2H Array
32296183
Intra
OTOP3 Q7RTS5 FAM210B Homo sapiens Q96KR6
Validated Y2H
32296183
Intra
OTOP3 Q7RTS5 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
Intra
OTOP3 Q7RTS5 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
Intra
OTOP3 Q7RTS5 COMT Homo sapiens P21964
Y2H Prey Pooling
32296183
Intra
OTOP3 Q7RTS5 COMT Homo sapiens P21964
Y2H Array
32296183
Intra
OTOP3 Q7RTS5 ZFYVE27 Homo sapiens Q5T4F4
Y2H Array
32296183
Intra
OTOP3 Q7RTS5 ZFYVE27 Homo sapiens Q5T4F4
Y2H Prey Pooling
32296183
Intra
OTOP3 Q7RTS5 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra
OTOP3 Q7RTS5 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra
OTOP3 Q7RTS5 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra
OTOP3 Q7RTS5 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS29534 OTOP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown