2. Gene
  3. ABLIM1 - actin binding LIM protein 1 Gene

ABLIM1 - actin binding LIM protein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ABLIM; LIMAB1; LIMATIN; abLIM-1

Gene ID: 3983 | Gene type: protein coding

About ABLIM1

Cytogenetic location: 10q25.3 Genomic coordinates (GRCh38): 10:114,431,110-114,801,373 (from NCBI)

This gene has 14 transcripts (splice variants), 132 orthologues and 3 paralogues. Ubiquitous expression in ovary (RPKM 50.7), heart (RPKM 50.1) and 23 other tissues.

Summary

This gene encodes a LIM zinc-binding domain-containing protein that binds to actin filaments and mediates interactions between actin and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2017]

ABLIM1 Products(26)

mRNA Protein Name
NM_001003407.2 NP_001003407.1 actin-binding LIM protein 1 isoform b
NM_001322882.2 NP_001309811.1 actin-binding LIM protein 1 isoform d
NM_001322883.2 NP_001309812.1 actin-binding LIM protein 1 isoform e
NM_001322884.3 NP_001309813.1 actin-binding LIM protein 1 isoform f
NM_001322885.3 NP_001309814.1 actin-binding LIM protein 1 isoform g
NM_001322886.3 NP_001309815.1 actin-binding LIM protein 1 isoform h
NM_001322887.2 NP_001309816.1 actin-binding LIM protein 1 isoform i
NM_001322888.2 NP_001309817.1 actin-binding LIM protein 1 isoform j
NM_001322889.2 NP_001309818.1 actin-binding LIM protein 1 isoform k
NM_001322890.2 NP_001309819.1 actin-binding LIM protein 1 isoform l
NM_001322891.2 NP_001309820.1 actin-binding LIM protein 1 isoform l
NM_001322892.2 NP_001309821.1 actin-binding LIM protein 1 isoform n
NM_001322893.2 NP_001309822.1 actin-binding LIM protein 1 isoform n
NM_001322894.2 NP_001309823.1 actin-binding LIM protein 1 isoform o
NM_001322895.2 NP_001309824.1 actin-binding LIM protein 1 isoform o
NM_001322896.2 NP_001309825.1 actin-binding LIM protein 1 isoform p
NM_001322897.2 NP_001309826.1 actin-binding LIM protein 1 isoform q
NM_001322898.2 NP_001309827.1 actin-binding LIM protein 1 isoform r
NM_001322899.2 NP_001309828.1 actin-binding LIM protein 1 isoform r
NM_001322900.2 NP_001309829.1 actin-binding LIM protein 1 isoform t
NM_001352440.1 NP_001339369.1 actin-binding LIM protein 1 isoform u
NM_001352441.1 NP_001339370.1 actin-binding LIM protein 1 isoform v
NM_001352442.2 NP_001339371.1 actin-binding LIM protein 1 isoform w
NM_001352443.2 NP_001339372.1 actin-binding LIM protein 1 isoform x
NM_002313.7 NP_002304.3 actin-binding LIM protein 1 isoform a
NM_006720.4 NP_006711.3 actin-binding LIM protein 1 isoform s

ABLIM1 Protein Structure

LIM

LIM: LIM domain (99 - 153)

LIM

LIM: LIM domain (158 - 209)

LIM

LIM: LIM domain (226 - 279)

LIM

LIM: LIM domain (285 - 328)

VHP

VHP: Villin headpiece domain (743 - 778)

  • 0
  • 200
  • 400
  • 600
  • 778 a.a.
Protein Preferred Names Protein Names

actin-binding LIM protein 1

actin-binding LIM protein family member 1

Related Diseases

Diseases Alias
Spermatogenic Failure, Y-Linked, 2

SPGFY2

Spermatogenic Failure, Nonobstructive, Y-Linked

Y-Linked Spermatogenic Failure 2

Azoospermia, Nonobstructive, Y-Linked

Oligozoospermia, Nonobstructive, Y-Linked

Oligospermia, Nonobstructive, Y-Linked

Spermatogenic Arrest, Y-Linked

Nonobstructive Y-Linked Spermatogenic Failure

Spermatogenic Failure Y-Linked 2

Azoospermia Non-Obstructive Y-Linked

Non-Obstructive Azoospermia And Infertility

Oligospermia Non-Obstructive Y-Linked

Oligozoospermia Non-Obstructive Y-Linked

Spermatogenic Arrest Y-Linked

Spermatogenic Failure Nonobstructive Y-Linked
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00106 ABLIM1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ABLIM1 VGNC VGNC:55931
Felis catus ABLIM1 VGNC VGNC:68486
Rattus norvegicus ABLIM1 RGD RGD:1565768
Macaca mulatta ABLIM1 VGNC VGNC:69587
Canis familiaris ABLIM1 VGNC VGNC:37478
Mus musculus ABLIM1 MGD MGI:1194500