NME3 - NME/NM23 nucleoside diphosphate kinase 3 Gene

Homo sapiens

Also known as NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2

Gene ID: 4832 | Gene type: protein coding

About NME3

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:1,770,320-1,771,543 (from NCBI)

This gene has 11 transcripts (splice variants), 177 orthologues and 8 paralogues. Ubiquitous expression in prostate (RPKM 24.8), fat (RPKM 18.6) and 25 other tissues.

Summary

Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in apoptotic process and nucleotide metabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

NME3 Products(1)

mRNA	Protein	Name
NM_002513.3	NP_002504.2	nucleoside diphosphate kinase 3 precursor

NME3 Protein Structure

NDK

0
100
169 a.a.

Protein Preferred Names

Protein Names

nucleoside diphosphate kinase 3

NDK 3

Related Diseases

Diseases

Alias

Lipase Deficiency, Combined

Lipoprotein Lipase Deficiency With Hepatic Triglyceride Lipase Deficiency	Lpl And Htgl Deficiency
Lpl And Hl Deficiency	Familial Lipase Maturation Factor 1 Deficiency
Lipase Deficiency Combined	Combined Lipase Deficiency
Familial Lmf1 Deficiency	CLD

Heinz Body Anemias

Heinz Body Anemia	Heinz Body Anemias, Alpha-
HEIBAN	Anemia, Heinz Body
Acquired Heinz Body Anemia

Zellweger Syndrome

Cerebrohepatorenal Syndrome	Zellweger Leukodystrophy
Zs	Congenital Iron Overload
Chr	Zws
Severe Pbd-Zsd	Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09374	NME3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	NME3	VGNC	VGNC:32126
Felis catus	NME3	VGNC	VGNC:107766
Macaca mulatta	NME3	VGNC	VGNC:75357
Rattus norvegicus	NME3	RGD	RGD:619879
Mus musculus	NME3	MGD	MGI:1930182
Canis familiaris	NME3	VGNC	VGNC:54050