GLS - glutaminase Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 488448

About GLS

Primary_assembly 37: 1,321,033-1,397,358 forward strand.ROS_Cfam_1.0:CM025136.1

This gene has 3 transcripts (splice variants), 305 orthologues and 1 paralogue.

GLS Products (2)

mRNA Protein Name
XM_038447420.1 XP_038303348.1 glutaminase kidney isoform, mitochondrial isoform X1
XM_038447419.1 XP_038303347.1 glutaminase kidney isoform, mitochondrial isoform X2

GLS Protein Structure

EF-hand_14

EF-hand_14: pfam17959 (149 - 232)

Glutaminase

Glutaminase: pfam04960 (254 - 538)

Ank_2

Ank_2: pfam12796 (567 - 659)

ANK

ANK: sd00045 (567 - 593)

ANK

ANK: sd00045 (595 - 627)

  • 0
  • 200
  • 400
  • 600
  • 680 a.a.
Protein Preferred Names Protein Names

glutaminase kidney isoform, mitochondrial

LOW QUALITY PROTEIN: glutaminase kidney isoform, mitochondrial

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-12248 Telaglenastat 99.82% Phase 2
HY-108917 Morphothiadin Inhibitor 99.79% Phase 2
HY-128357 Ibezapolstat Inhibitor 98.0% Phase 2
HY-12248A Telaglenastat hydrochloride 98.03% Phase 2
HY-P2760 Glutaminase Control / Phase 2
HY-108917A Morphothiadin mesylate Inhibitor / Phase 2
HY-128357A Ibezapolstat hydrochloride Inhibitor / Phase 2
HY-103671 IPN60090 Inhibitor 98.96% Phase 1
HY-103671A IPN60090 dihydrochloride Inhibitor 99.68% Phase 1
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99109 Zimberelimab Inhibitor 99.90% Phase 3

Pre-clinical Phase

Bioactive Molecules (20)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-136704 GLS1 Inhibitor-1 Inhibitor 98.59% Unkown
HY-79583 Glutaminase-IN-3 Inhibitor 99.88% Unkown
HY-150109A Purinostat Inhibitor 98.04% Unkown
HY-144666 GLS-1-IN-1 Inhibitor 99.83% Unkown
HY-RS05500 GLS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-151434 GLS1 Inhibitor-6 / Unkown
HY-146616 GLS1 Inhibitor-3 Inhibitor / Unkown
HY-146617 GLS1 Inhibitor-4 / Unkown
HY-146658 Glutaminase-IN-4 Inhibitor / Unkown
HY-148241 A-446 Inhibitor / Unkown
HY-152207 LWG-301 / Unkown
HY-155138 GLS1 Inhibitor-7 Inhibitor / Unkown
HY-174211 JNK-IN-23 Inhibitor / Unkown
HY-179003 mTOR/GLS1-IN-1 / Unkown
HY-181890 TRG-192 Inhibitor / Unkown
HY-RS05501 Gls Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05502 Gls Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05503 GLS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17808 Gls2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24276 Gls2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990976 Brivestobart 99.198% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens GLS NCBI NCBI:2744