WRAP73 - WD repeat containing, antisense to TP73 Gene

Also Known as WDR8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 49856

Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 Amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, Apoptosis, and gene regulation. Studies of the related mouse protein suggest that the encoded protein may play a role in the process of ossification. [provided by RefSeq, Mar 2009]
Ubiquitous expression in bone marrow (RPKM 7.8), testis (RPKM 7.1) and 25 other tissues.

WRAP73 Products (1)

mRNA Protein Name
NG_033937.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25036637 GOA
Biological Process GO Annotation Evidence References Source
involved in mitotic spindle assembly IMP
IMP: Inferred from mutant phenotype
26545777 GOA
involved in positive regulation of non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
26545777 GOA
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
21399614 GOA
located in ciliary basal body IDA
IDA: Inferred from direct assay
26545777 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WRAP73 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
WRAP73 Q9P2S5 SSX2IP Homo sapiens Q9Y2D8
IF
26545777
Intra
WRAP73 Q9P2S5 SSX2IP Homo sapiens Q9Y2D8
Anti Tag CoIP
26545777
Intra
WRAP73 Q9P2S5 SSX2IP Homo sapiens Q9Y2D8
Anti Tag CoIP
33961781
Intra
WRAP73 Q9P2S5 SSX2IP Homo sapiens Q9Y2D8
Anti Tag CoIP
26638075
Intra
WRAP73 Q9P2S5 SSX2IP Homo sapiens Q9Y2D8
Confocal
26675238
Intra
WRAP73 Q9P2S5 NUDC Homo sapiens Q9Y266
Anti Tag CoIP
33961781
Intra
WRAP73 Q9P2S5 NUDC Homo sapiens Q9Y266
Lumier
25036637
Cross
WRAP73 Q9P2S5 Ssx2ip Mus musculus Q8VC66
Confocal
26675238
Cross
WRAP73 Q9P2S5 Ssx2ip Mus musculus Q8VC66
Anti Tag CoIP
26675238
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15846 WRAP53 Human Pre-designed siRNA Set A Pre-designed Set / Unkown