Ssx2ip - synovial sarcoma, X 2 interacting protein Gene

Also Known as Adip

Species: Mus musculus

Gene Type: protein coding
Gene ID: 99167

Summary

Predicted to enable protein domain specific binding activity. Acts upstream of or within regulation of Rac protein signal transduction and regulation of cell motility. Located in cell leading edge; centriolar satellite; and ciliary basal body. Orthologous to human SSX2IP (SSX family member 2 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Ssx2ip Products (19)

mRNA Protein Name
NM_001253768.2 NP_001240697.1 afadin- and alpha-actinin-binding protein isoform b
NM_001253769.2 NP_001240698.1 afadin- and alpha-actinin-binding protein isoform b
NM_001253770.2 NP_001240699.1 afadin- and alpha-actinin-binding protein isoform b
NM_001355661.1 NP_001342590.1 afadin- and alpha-actinin-binding protein isoform a
NM_001411104.1 NP_001398033.1 afadin- and alpha-actinin-binding protein isoform a
NM_001411105.1 NP_001398034.1 afadin- and alpha-actinin-binding protein isoform a
NM_001411107.1 NP_001398036.1 afadin- and alpha-actinin-binding protein isoform a
NM_001411108.1 NP_001398037.1 afadin- and alpha-actinin-binding protein isoform a
NM_001411109.1 NP_001398038.1 afadin- and alpha-actinin-binding protein isoform a
NM_001411110.1 NP_001398039.1 afadin- and alpha-actinin-binding protein isoform b
NM_001411114.1 NP_001398043.1 afadin- and alpha-actinin-binding protein isoform b
NM_001411115.1 NP_001398044.1 afadin- and alpha-actinin-binding protein isoform b
NM_001411116.1 NP_001398045.1 afadin- and alpha-actinin-binding protein isoform c
NM_001411117.1 NP_001398046.1 afadin- and alpha-actinin-binding protein isoform c
NM_001411118.1 NP_001398047.1 afadin- and alpha-actinin-binding protein isoform c
NM_001411119.1 NP_001398048.1 afadin- and alpha-actinin-binding protein isoform d
NM_001411120.1 NP_001398049.1 afadin- and alpha-actinin-binding protein isoform d
NM_001411121.1 NP_001398050.1 afadin- and alpha-actinin-binding protein isoform e
NM_138744.4 NP_620083.1 afadin- and alpha-actinin-binding protein isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12446711 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of Rac protein signal transduction IMP
IMP: Inferred from mutant phenotype
22027834 MGI
acts upstream of or within regulation of cell motility IMP
IMP: Inferred from mutant phenotype
22027834 MGI
Cellular Component GO Annotation Evidence References Source
located in cell leading edge IDA
IDA: Inferred from direct assay
22027834 MGI
located in centriolar satellite IDA
IDA: Inferred from direct assay
24356449 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
24356449 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

afadin- and alpha-actinin-binding protein

  • afadin DIL domain-interacting protein

  • synovial sarcoma, X breakpoint 2 interacting protein

Ssx2ip Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Ssx2ip Q8VC66 ACTN1 Homo sapiens P12814
Anti Tag CoIP
12446711
Cross
Ssx2ip Q8VC66 Afdn Rattus norvegicus O35889
Anti Tag CoIP
12446711
Cross
Ssx2ip Q8VC66 Afdn Rattus norvegicus O35889
Y2H
12446711
Cross
Ssx2ip Q8VC66 Afdn Rattus norvegicus O35889
Pull Down
12446711
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13838 SSX2IP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ssx2ip NCBI NCBI:117178